NYMU Taipei/Materials/Two component system for glucose sensing in E. coli

From 2007.igem.org

  • glucose causes the expression of cps genes (Capsular <a class="external text" title="http://en.wikipedia.org/wiki/Polysaccharide" rel="nofollow" href="http://en.wikipedia.org/wiki/Polysaccharide">Polysaccharide</a> synthesis) annotated in KEGG TCS
    • b2048: cpsG (rfbK, manB)
      • phosphomannomutase [EC:5.4.2.8]
      • KO: K01840  phosphomannomutase
      • PATH: eco00051  Fructose and mannose metabolism
      • complement(2119633..2121003)
    • b2049: cpsB (mni, manC, rfbM)
      • mannose-1-phosphate guanyltransferase [EC:2.7.7.22]
      • KO: K00971  mannose-1-phosphate guanylyltransferase
      • PATH: eco00051  Fructose and mannose metabolism
      • complement(2121108..2122544)
  • RcsF, RcsC are sensory proteins on membrane
    • b0196: rcsF
      • <a class="image" title="Image:RcsF.png" href="../../index.php/Image:RcsF.png">File:RcsF.png
        </a>
      • <a class="image" title="Image:RcsF domain.png" href="../../index.php/Image:RcsF_domain.png">File:RcsF domain.png
        </a>
      • regulator in colanic acid synthesis; interacts with RcsB
      • KO: K06080  RcsF protein
      • PATH: eco02020  Two-component system - General
      • complement(219591..219995)
    • b2218: rcsC
      • <a class="image" title="Image:RcsC domain.png" href="../../../index.php/Image:RcsC_domain.png">File:RcsC.png</a>
      • <a class="image" title="Image:RcsC domain.png" href="../../../index.php/Image:RcsC_domain.png">File:RcsC domain.png</a>
      • hybrid sensory histidine kinase in two-component regulatory system with RcsB, regulates capsule biosynthesis, cell division genes, OsmC expression [EC:2.7.13.3]
      • KO: K07677  two-component system, NarL family, capsular synthesis sensor histidine kinase RcsC
      • PATH: eco02020  Two-component system - General
      • PATH: eco02021  Two-component system - Organism-specific
      • complement(2315049..2317898)
      • Pfam: Staphostatin_B HisKA HATPase_c Response_reg
      • PROSITE: RESPONSE_REGULATORY HIS_KIN
  • RcsA, RcsB are activator of cps operon
    • b1951: rcsA (cpsR)
    • b2217: rcsB
      • positive response regulator for colanic capsule biosynthesis, (sensor, RcsC)
      • KO: K07687  two-component system, NarL family, captular synthesis response regulator RcsB
      • PATH: eco02020  Two-component system
      • 2314199..2314849
    • b2218: rcsC
      • hybrid sensory histidine kinase in two-component regulatory system with RcsB, regulates capsule biosynthesis, cell division genes, OsmC expression [EC:2.7.13.3]
      • KO: K07677  two-component system, NarL family, capsular synthesis sensor histidine kinase RcsC
      • PATH: eco02020  Two-component system
      • complement(2315049..2317898)
  • The Rcs phosphorelay
  • The OmpR-EnvZ two-component system