I am a physicist, assistant professor at the University Denis Diderot in Paris (for the moment visitor scientist at CNRS in the department Génétiques des Génomes at the Pasteur Institute). I am interested in self-organization, out of equilibrium dynamics, and the logic of cellular computation. My research these last years is on structure and dynamics of regulatory networks. In particular I am interested in the interplay between genome architecture, spatial organization of the cell and dynamical properties of cell functions. Genomic context and architecture possibly determines or optimizes the output of artificial genetic networks.