http://2007.igem.org/wiki/index.php?title=Basic_assumptions&feed=atom&action=historyBasic assumptions - Revision history2024-03-28T12:06:10ZRevision history for this page on the wikiMediaWiki 1.16.5http://2007.igem.org/wiki/index.php?title=Basic_assumptions&diff=26298&oldid=prevGiov1984 at 14:38, 16 October 20072007-10-16T14:38:03Z<p></p>
<p><b>New page</b></p><div>We realized a reaction network as a system of ODEs. Clearly we need to guess working hypothesis:<br />
*Component concentrations don't vary with respect to space<br />
Whether it is a good assumption depends on time and space scales. In a yeast cell molecular diffution is sufficiently fast to mix proteins in less than one minute<br />
*Component concentrations are continuous functions of time<br />
This is true if the number of molecules of each species in the reaction volume is sufficiently large<br />
<br />
Other important assumptions are the following:<br />
*Transcription factor timescales are much larger than protein-protein interactions timescales<br />
*Input changes are very rapid<br />
We will use this assumptions to simplify our modeling<br />
<br />
ODEs are very useful to represent molecular interaction. Indeed, applying a simple set of rules we can represent arbitrarily complex reaction networks as a set of coupled ODEs!</div>Giov1984