Cell Integration

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(Cell Integration)
 
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== Cell Integration ==
== Cell Integration ==
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Increased levels or strength of adherins will cause cells to penetrate into tissue with lower levels of cell-cell interacting molecules.
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Increased levels or strength of adherins will cause cells to penetrate into tissue with lower levels of cell-cell interacting molecules.  Activation of signaling by binding of one of our signaling targeting chimeric proteins will trigger expression of the cell-cell adhesion molecule N-Cadherin which was inserted downstream of a minimal promoter with lexA operators. Increased N-Cadherin expression may result in penetration of the new cardiomyocytes into the myocardium.
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[[Image:adherins.jpg]]
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Ilustrative data demonstrating the basic principle from the literature:
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[[Image:adherins.gif]]

Latest revision as of 04:12, 27 October 2007

Cell Integration

Increased levels or strength of adherins will cause cells to penetrate into tissue with lower levels of cell-cell interacting molecules. Activation of signaling by binding of one of our signaling targeting chimeric proteins will trigger expression of the cell-cell adhesion molecule N-Cadherin which was inserted downstream of a minimal promoter with lexA operators. Increased N-Cadherin expression may result in penetration of the new cardiomyocytes into the myocardium.

Ilustrative data demonstrating the basic principle from the literature: Adherins.gif