Samantha Liang

From 2007.igem.org

Revision as of 20:20, 8 June 2007 by Samanthaliang (Talk | contribs)
(diff) ← Older revision | Latest revision (diff) | Newer revision → (diff)

Berkeley.jpg
Addressable Conjugation in Bacterial Networks

Networks of interacting cells provide the basis for neural learning. We have developed the process of addressable conjugation for communication within a network of E. coli bacteria. Here, bacteria send messages to one another via conjugation of plasmid DNAs, but the message is only meaningful to cells with a matching address sequence. In this way, the Watson Crick base-pairing of addressing sequences replaces the spatial connectivity present in neural systems. To construct this system, we have adapted natural conjugation systems as the communication device. Information contained in the transferred plasmids is only accessable by "unlocking" the message using RNA based 'keys'. The resulting addressable conjugation process is being adapted to construct a network of NAND logic gates in bacterial cultures. Ultimately, this will allow us to develop networks of bacteria capable of trained learning.
The presentation of our results for the 2006 Jamboree is available at the [http://parts2.mit.edu/wiki/index.php/University_of_California_Berkeley_2006 iGEM Website]

The Berkeley iGEM team very gratefully acknowledges the generous support of Microsoft, which helped make our team members' participation possible.


Resources Team


Undergrads Advisors
John Dueber
[http://www.openwetware.org/wiki/User:JCAnderson Christopher Anderson]
Adam Arkin
Jay Keasling

Teaching Assistants
Farnaz Nowroozi
Amin Hajimorad
Rickey Bonds

Undergraduate Researchers
Arthur Yu
Austin Day
David Tulga
Kristin Doan
Samantha Liang
Vaibhavi Umesh
Kristin Fuller


High School Students

Coming Soon!

News Tools


lab calendar

Team Resources

[http://spreadsheets.google.com/ccc?key=pUQEpr4ZqU9TxjeURaNm1Vw Oligo List Spreadsheet]
[http://partsregistry.org/cgi/partsdb/pgroup.cgi?pgroup=iGEM2007&group=Berkeley_UC Our BioBrick Parts]
All construction files
All sequencing files

Tools and Guides
[http://www.openwetware.org/wiki/Arking:JCAOligoTutorialHome Biobricks and Cloning Tutorials]
[http://pir.georgetown.edu/pirwww/search/pairwise.shtml Pairwise Alignment Online]
[http://en.wikipedia.org/wiki/Help:Wikitext_examples Wiki Formatting Guide]


Team Notebooks
John Dueber Notebook
Christopher Anderson Notebook
Farnaz Nowroozi Notebook
Amin Hajimorad Notebook
Rickey Bonds Notebook
Arthur Yu's 1337 Notebook
Austin Day Notebook
David Tulga Notebook
Kristin Doan Notebook
Samantha Liang Notebook
Vaibhavi Umesh Notebook
Kristin Fuller Notebook



Resources Project


Addressable Cell-to-Cell Communication

  • Berkeley 2005 'Jamboree'
  • [http://parts2.mit.edu/wiki/index.php/UC_Berkeley_2005 2005 Project]
  • [http://partsregistry.org/cgi/partsdb/pgroup.cgi?pgroup=iGEM2006&group=Berkeley 2006 Parts List]

Useful Links

  • iGEM
  • [http://parts2.mit.edu/wiki/index.php/University_of_California_Berkeley_2006 UC Berkeley iGEM wiki]
  • [http://parts2.mit.edu/wiki/index.php/Main_Page iGEM wiki]
  • [http://partsregistry.org/Main_Page Registry of Standard Biological Parts]
  • [http://parts2.mit.edu/r/parts/partsdb/pgroup.cgi?pgroup=iGEM&group=iGEM_Berkeley 2005 Biobricks]
  • iGEM2006 Distribution compiled list
  • [http://parts2.mit.edu/wiki/index.php/University_of_California_Berkeley_2006 | iGEM site]