USTC

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=== Our Project:<BR>Extensible Logic Circuit in Bacteria ===
=== Our Project:<BR>Extensible Logic Circuit in Bacteria ===
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Logic Artificial Biologic Circuit (ABC) and logic Integrated Circuit (IC) are both composed by logic gates and wires. Now we are enjoying the advantage of Ultra Large Scale IC (ULSI), but at least today we cannot implement a somewhat large logic ABC containing several levels of logic gates in actual experiments.
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Logic Artificial Biologic Circuit (ABC) and logically Integrated Circuit (IC) are both composed by logic gates and wires. Now we are enjoying the advantages of Ultra Large Scale IC (ULSI), but at least till now we cannot implement a somewhat large logic ABC containing several levels of logic gates in real experiments.
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Our project is to provide a new methodology for building up fully extensible logic ABC. We are going to produce biologic logic gates such as NAND, NOR, NOT for some biological conveniences. In other words, modern logic IC are built upon these three gates-- NAND, NOR and NOT. Logic gates are only the basic components of logic IC, on the other hand, the more important factors we think which make IC to be easily enlarged are: reducing the size, power and response time of components; tuning components to eliminate interference; calibrating components for interconnection. Cis-acting elements may provide smaller scale than trans-acting ones, while the other two factors can be achieved by novelly designed wires and standardization. We will also demonstrate an ABC made by these biologic logic gates.
+
Our project is to provide a new method for building up fully extensible logic ABC. We are going to produce biological logic gates such as NAND, NOR, NOT for some biological convenience on which modern logic IC are exactly built. Logic gates are just the basic components of logic IC. Factors considered more important to let IC easily enlarged are size reduction, power and response time of components; tuning components to eliminate interference; calibrating components for interconnection. Cis-acting elements may present smaller scale than trans-acting ones, while the other two factors can be achieved by novelly designed wires and standardization. We will also demonstrate an ABC made by these biological logic gates.
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This ABC may not be large, but the important factors we implement in it will naturally make it fully extensible. IC has been born for 50 years and how hugely it impacts our modern life! So, what about biologic logic circuit in next 50 years? A new world is waiting...
+
Such ABC may not be large, but the important factors we implement in it will naturally make it fully extensible. IC has existed for 50 years.How huge its impact is on our modern lives! So, what about the  biological logic circuits in the next 50 years? A new world is waiting us...

Revision as of 09:16, 2 August 2007


USTC Logo.png

Our Project:
Extensible Logic Circuit in Bacteria

Logic Artificial Biologic Circuit (ABC) and logically Integrated Circuit (IC) are both composed by logic gates and wires. Now we are enjoying the advantages of Ultra Large Scale IC (ULSI), but at least till now we cannot implement a somewhat large logic ABC containing several levels of logic gates in real experiments.

Our project is to provide a new method for building up fully extensible logic ABC. We are going to produce biological logic gates such as NAND, NOR, NOT for some biological convenience on which modern logic IC are exactly built. Logic gates are just the basic components of logic IC. Factors considered more important to let IC easily enlarged are size reduction, power and response time of components; tuning components to eliminate interference; calibrating components for interconnection. Cis-acting elements may present smaller scale than trans-acting ones, while the other two factors can be achieved by novelly designed wires and standardization. We will also demonstrate an ABC made by these biological logic gates.

Such ABC may not be large, but the important factors we implement in it will naturally make it fully extensible. IC has existed for 50 years.How huge its impact is on our modern lives! So, what about the biological logic circuits in the next 50 years? A new world is waiting us...


DSCN1243.png

From left to right
Back row: Zhao Yun, Liu Ziqing, Ma Xiaoyu
Front row: Ma Rui, Su Xiaofeng, Ding Bo, Zhan Jian

Events

01/08/2007
Ma Rui: There is a mistake in my preparing X-Gal solution. Please rework your correlative experiments. Sorry!

30/07/2007
First designed repressors. Good work, Bo and Xiaofeng!

22/06/2007
Sruggling for the final-examinations.

01/06/2007
Primary experiments begin around this day.

Previous

Tasks


PoPS Convertors

Biologic Logic Gates

Promoter Designing

Lac Repressor Redesigning

Fluorescent Reporters

All Things Together Linking

Wiki Construction

Presentation and Poster


Members

Graduates:
Zhan Jian
Ding Bo
Ma Rui
Ma Xiaoyu

Undergraduates:
Su Xiaofeng
Liu Ziqing
Zhao Yun

Faculty Advisors:
Prof. HY Liu
Prof. JR Wu
Prof. ZH Hou

Resources

Modeling Utilities

Protocols

Promoter Design

Service Providers

Gallery

Team Photos

Laboratory

USTC Photos

Huangshan Mountain

Links

iGEM standard parts' catalog

Univ. of Sci. and Tech. of China

iGEM China Group


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