Virginia Tech

From 2007.igem.org

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'''<html><center><font size="5" color="#8b0000">The 2007 Virginia Tech iGEM team welcomes you to our Wiki! </font><br><br><font size="4">Look around to learn about our 2007 project: Engineering an Epidemic.</font></center></html>'''
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[[Image:InfectionMatch.png|thumb|300px|center|'''Matching infection in a single population.''' Go to our
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[[Virginia_Tech/model|modeling page]] to learn more.]]
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<html><center></html><h3>Modeling and Epidemiology</h3>
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This year, our team worked on engineering an epidemic by simulating the spread of an infection in a biological model system. Our model has multiple levels, which we matched to experimental data one at a time. Click [[Virginia_Tech/model|here]] to read more about our modeling experience.<html></center></html>
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[[Image:Ecoli phage.PNG|thumb|center|350px|'''''E.coli'' infected with fluorescent phage.''' This cell is lytic: the green spots are new phage particles being constructed prior to lysis.]]
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<html><center></html><h3>Using a Biological Model System</h3>
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λ phage and ''E. coli'' constitute our model system. λ phage has two infection pathways: lysis and lysogeny. A lytic cell will burst shortly after infection, while a lysogenic cell stays dormant. In order to find out which pathway had been chosen in our bacteria, we constructed a [[Virginia_Tech/plasmid_design|reporter plasmid]].<html></center></html>
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<h1>We would like to thank our sponsors:</h1>
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Latest revision as of 04:03, 26 October 2007

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The 2007 Virginia Tech iGEM team welcomes you to our Wiki!

Look around to learn about our 2007 project: Engineering an Epidemic.


Matching infection in a single population. Go to our modeling page to learn more.

Modeling and Epidemiology

This year, our team worked on engineering an epidemic by simulating the spread of an infection in a biological model system. Our model has multiple levels, which we matched to experimental data one at a time. Click here to read more about our modeling experience.

E.coli infected with fluorescent phage. This cell is lytic: the green spots are new phage particles being constructed prior to lysis.

Using a Biological Model System

λ phage and E. coli constitute our model system. λ phage has two infection pathways: lysis and lysogeny. A lytic cell will burst shortly after infection, while a lysogenic cell stays dormant. In order to find out which pathway had been chosen in our bacteria, we constructed a reporter plasmid.



We would like to thank our sponsors: