Virginia Tech

From 2007.igem.org

(Difference between revisions)
m
m
 
(6 intermediate revisions not shown)
Line 1: Line 1:
<html><center></html><!--first table: Title-->
<html><center></html><!--first table: Title-->
-
{| style="border: 2px solid #FFCC66; width: 750px; color: #000000; background-color: #FFFFFF;"
+
{| style="border: 0px solid #FFCC66; width: 750px; color: #000000; background-color: #FFFFFF;"
Line 7: Line 7:
<center>[[Image:Title_bar.JPG]]</center>
<center>[[Image:Title_bar.JPG]]</center>
-
<center><h3><font color="#8b0000"> This wiki is under construction! While you’re waiting, check out our externally hosted wiki [https://wiki.vbi.vt.edu/display/SBGi/iGEM+2007 here].
 
-
</font></h3></center>
 
|}
|}
Line 54: Line 52:
|}<html></center></html>
|}<html></center></html>
-
<!--third table: Content-->
+
<!--third table: Content 1-->
{| cellspacing="0px" border="0" style="width: 880px; color: #000000; background-color: #FFFFFF;"
{| cellspacing="0px" border="0" style="width: 880px; color: #000000; background-color: #FFFFFF;"
<!--first cell of the third table: Space-->
<!--first cell of the third table: Space-->
-
| style="width: 50px; background-color: #FFFFFF" |
+
| style="width: 0px; background-color: #FFFFFF" |
-
<!--second cell of the third table: Content-->
+
<!--second cell of the third table: Content 1-->
| style="padding: 20px; background-color: #FFFFFF;" |
| style="padding: 20px; background-color: #FFFFFF;" |
-
The Virginia Tech iGEM project for 2007 is to engineer an epidemic. This will allow us to model and observe epidemic development within and between populations. By modeling and observing epidemic development, we hope to be able to understand events from the beginning of an epidemic. We will be able to do this by designing a network for the spread of infection. Our model will be multi-scaled and will include modeling a bacterial growth curve, modeling an infection of a single population, and modeling a muliple population infection. After developing the models, we will be able to verify it experimentally.
 
-
Our project is particularly important because it is important to be able to predict early whether or not an infection will develop into an epidemic. It is important to know how to localize an infection to prevent the development of an epidemic. By modeling and experimentally testing the effects of air traffic on an epidemic, we can determine at what point an infection becomes an epidemic.  
+
'''<html><center><font size="5" color="#8b0000">The 2007 Virginia Tech iGEM team welcomes you to our Wiki! </font><br><br><font size="4">Look around to learn about our 2007 project: Engineering an Epidemic.</font></center></html>'''
 +
 
 +
 
 +
 
 +
<!--nested table: Content 2-->
 +
{| cellspacing="0px" border="0" style="width: 880px; color: #000000; background-color: #FFFFFF;"
 +
 
 +
<!--first cell of the nestedtable: Space-->
 +
| style="width: 50px; background-color: #FFFFFF" |
 +
 
 +
<!--second cell of the nestedtable: left column-->
 +
| style="padding: 20px; width: 400px; background-color: #FFFFFF" |
 +
 
 +
[[Image:InfectionMatch.png|thumb|300px|center|'''Matching infection in a single population.''' Go to our
 +
[[Virginia_Tech/model|modeling page]] to learn more.]]
 +
 
 +
<html><center></html><h3>Modeling and Epidemiology</h3>
 +
This year, our team worked on engineering an epidemic by simulating the spread of an infection in a biological model system. Our model has multiple levels, which we matched to experimental data one at a time. Click [[Virginia_Tech/model|here]] to read more about our modeling experience.<html></center></html>
 +
 
 +
<!--third cell of the nested table: divider-->
 +
| style="width: 5px; background-color: #FFFFFF;" |
 +
 
 +
<!--fourth cell of the nested table: right column-->
 +
| style="padding: 20px; width: 400px; background-color: #FFFFFF;" |
 +
 
 +
[[Image:Ecoli phage.PNG|thumb|center|350px|'''''E.coli'' infected with fluorescent phage.''' This cell is lytic: the green spots are new phage particles being constructed prior to lysis.]]
-
After matching our models to our experimental data, we hope to be able to publish some of our findings.  
+
<html><center></html><h3>Using a Biological Model System</h3>
 +
λ phage and ''E. coli'' constitute our model system. λ phage has two infection pathways: lysis and lysogeny. A lytic cell will burst shortly after infection, while a lysogenic cell stays dormant. In order to find out which pathway had been chosen in our bacteria, we constructed a [[Virginia_Tech/plasmid_design|reporter plasmid]].<html></center></html>
|}
|}
-
<!--fourth table: Sponsors-->
+
 
 +
 
 +
<!--fourth table: Divider-->
{| cellspacing="0px" border="0" style="width: 880px; color: #000000; background-color: #FFFFFF;"
{| cellspacing="0px" border="0" style="width: 880px; color: #000000; background-color: #FFFFFF;"
<!--first cell of the fourth table: Space-->
<!--first cell of the fourth table: Space-->
-
| style="padding: 5px; width: 0px; background-color: #FFFFFF; border: 0px solid #000000;" |
+
| style="padding: 5px; width: 50px; background-color: #FFCC66; border: 0px solid #000000;" |
-
<!--second cell of the fourth table: Sponsors-->
+
|}
-
| style="padding: 5px; background-color: #FFFFFF; border: 2px solid #000000;" |
+
-
<html><center><h1>We would like to thank our sponsors:</h1></center></html>
 
-
<html><center></html><!--first nested table: first line-->
 
-
{| cellspacing="0px" border="0" style="color: #000000; background-color: #FFFFFF;"
 
-
<!--first cell of the first nested table: Third Security-->
+
<!--fifth table: Sponsors-->
 +
{| cellspacing="0px" border="0" style="width: 880px; color: #000000; background-color: #FFFFFF;"
 +
 
 +
<!--first cell of the fifth table: Space-->
 +
| style="padding: 5px; width: 50px; background-color: #FFFFFF; border: 0px solid #000000;" |
 +
 
 +
<!--second cell of the fifth table: Other Sponsors-->
| style="padding: 5px; background-color: #FFFFFF; border: 0px solid #000000;" |
| style="padding: 5px; background-color: #FFFFFF; border: 0px solid #000000;" |
-
<html><a href="http://www.thirdsecurity.com"><img src="https://static.igem.org/mediawiki/2007/a/a4/Sponsor_3rdsec2.JPG" width="200">
+
<h1>We would like to thank our sponsors:</h1>
-
<br></br><img src="https://static.igem.org/mediawiki/2007/6/65/Sponsor_3rdsec1.JPG" width="200"></a></html>
+
 
 +
<html><center></html><!--first nested table: first line-->
 +
{| cellspacing="0px" border="0" style="color: #000000; background-color: #FFFFFF;"
<!--second cell of the first nested table: DNA 2.0-->
<!--second cell of the first nested table: DNA 2.0-->
Line 94: Line 123:
<html><a href="http://www.dnatwopointo.com">
<html><a href="http://www.dnatwopointo.com">
-
<img src="https://static.igem.org/mediawiki/2007/c/ce/DNA20_logo.jpg" width="200"></a></html>
+
<img src="https://static.igem.org/mediawiki/2007/c/ce/DNA20_logo.jpg" width="150"></a></html>
<!--third cell of the first nested table: VBI-->
<!--third cell of the first nested table: VBI-->
Line 100: Line 129:
<html><center><a href="http://www.vbi.vt.edu">
<html><center><a href="http://www.vbi.vt.edu">
-
<img src="https://static.igem.org/mediawiki/2007/b/b4/Logo_VBI.JPG" width="120"></a></center></html>
+
<img src="https://static.igem.org/mediawiki/2007/b/b4/Logo_VBI.JPG" width="150"></a></center></html>
-
|}
+
<!--fourth cell of the first nested table: VT-->
-
 
+
-
<!--second nested table: second line-->
+
-
{| cellspacing="0px" border="0" style="width: 880px; color: #000000; background-color: #FFFFFF;"
+
-
 
+
-
<!--first cell of the second nested table: VT-->
+
| style="padding: 5px; background-color: #FFFFFF; border: 0px solid #000000;" |
| style="padding: 5px; background-color: #FFFFFF; border: 0px solid #000000;" |
<html><a href="http://www.vt.edu">
<html><a href="http://www.vt.edu">
-
<img src="https://static.igem.org/mediawiki/2007/b/b4/VTsponsor_logo.JPG" width="200"></a></html>
+
<img src="https://static.igem.org/mediawiki/2007/b/b4/VTsponsor_logo.JPG" width="150"></a></html>
-
<!--second cell of the second nested table: VT-COE-->
+
|}<html><center></html>
-
| style="padding: 5px; background-color: #FFFFFF; border: 0px solid #000000;" |
+
-
<html><a href="http://www.eng.vt.edu/main/index.php">
 
-
<img src="https://static.igem.org/mediawiki/2007/6/62/Logo_COE.JPG" width="200"></a></html>
 
-
<!--third cell of the second nested table: VT-COS-->
+
<!--third cell of the fifth table: Third Security-->
-
| style="padding: 5px; background-color: #FFFFFF; border: 0px solid #000000;" |
+
| style="padding: 5px; width: 0px; background-color: #FFFFFF; border: 0px solid #000000;" |
-
<html><a href="http://www.cos.vt.edu">
+
<html><a href="http://www.thirdsecurity.com"><center><img src="https://static.igem.org/mediawiki/2007/a/a4/Sponsor_3rdsec2.JPG" width="150">
-
<img src=" https://static.igem.org/mediawiki/2007/d/d3/COS_logo.jpg" width="200"></a></html>
+
<br></br><img src="https://static.igem.org/mediawiki/2007/6/65/Sponsor_3rdsec1.JPG" width="200"></center></a></html>
-
<!--fourth cell of the second nested table: VT-CALS-->
 
-
| style="padding: 5px; background-color: #FFFFFF; border: 0px solid #000000;" |
 
-
<html><a href="http://www.cals.vt.edu">
 
-
<img src="https://static.igem.org/mediawiki/2007/c/c7/Logo_CALS.JPG" width="200"></a></html>
 
-
 
-
|}<html><center></html>
 
|}
|}

Latest revision as of 04:03, 26 October 2007

Title bar.JPG

Dot1.JPG

Dot1.JPG

Dot1.JPG

Dot1.JPG

Dot1.JPG

The 2007 Virginia Tech iGEM team welcomes you to our Wiki!

Look around to learn about our 2007 project: Engineering an Epidemic.


Matching infection in a single population. Go to our modeling page to learn more.

Modeling and Epidemiology

This year, our team worked on engineering an epidemic by simulating the spread of an infection in a biological model system. Our model has multiple levels, which we matched to experimental data one at a time. Click here to read more about our modeling experience.

E.coli infected with fluorescent phage. This cell is lytic: the green spots are new phage particles being constructed prior to lysis.

Using a Biological Model System

λ phage and E. coli constitute our model system. λ phage has two infection pathways: lysis and lysogeny. A lytic cell will burst shortly after infection, while a lysogenic cell stays dormant. In order to find out which pathway had been chosen in our bacteria, we constructed a reporter plasmid.



We would like to thank our sponsors: