Waterloo

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University of Waterloo iGEM Team

Our Team

The UW iGEM team is a very interdisciplinary group. Our team members span the four faculties of Science, Mathematics, Engineering, and Applied Health Sciences and include the programs of Biology, Health Studies, Computer Science, Bioinformatics, Computer Engineering, Electrical Engineering, Chemical Engineering, and Mathematical Physics at undergraduate and graduate levels. Even our professor advisors are cross-appointed to two other faculties. Our diverse backgrounds bring together a wide range of skills and ideas to the iGEM project. iGEM is giving us the opportunity to apply the skills learned in our lectures and labs to real life applications in molecular biology and biotechnology.

Our Design

Our project is a light and chemical controlled full adder.

The Inputs

We will be using one light input in the form of red light and two chemical inputs. The red light will be detected by the previously used Cph1/EnvZ fusion protein (BBa_I15010).

The chemical inputs to be used are currently being determined.

We have chosen to use light as an input for the reasons that it does not require altering the media, it can be turned on and off rapidly, and it has extremely high resolution and accuracy.

The Logic Gates

CURRENTLY IN PROGRESS

Supporters

We would like to thank:

Faculty of Science — Faculty of Math — Faculty of Engineering

Waterloo Engineering Endowment Fund — Mathematics Endowment Fund

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 == Our Team ==
-The UW iGEM team is a very interdisciplinary group. Our team members span the four faculties of Science, Mathematics, Engineering, and Applied Health Sciences and include the programs of Biology, Health Studies, Computer Science, Bioinformatics, Computer Engineering, Electrical Engineering, Chemical Engineering, and Mathematical Physics at undergraduate and graduate levels. Even our professor advisors are cross-appointed to two other faculties.  Our diverse backgrounds bring together a wide range of skills and ideas to the iGEM project. iGEM is giving us the opportunity to learn.
+The UW iGEM team is a very interdisciplinary group. Our team members span the four faculties of Science, Mathematics, Engineering, and Applied Health Sciences and include the programs of Biology, Health Studies, Computer Science, Bioinformatics, Computer Engineering, Electrical Engineering, Chemical Engineering, and Mathematical Physics at undergraduate and graduate levels. Even our professor advisors are cross-appointed to two other faculties.  Our diverse backgrounds bring together a wide range of skills and ideas to the iGEM project. iGEM is giving us the opportunity to apply the skills learned in our lectures and labs to real life applications in molecular biology and biotechnology.
 == Our Design ==
-Our project is a light-controlled 1-bit adder.
+Our project is a light and chemical controlled full adder.
 === The Inputs ===
-We will be using red light as one of the inputs and blue light as the other.  The red light will be detected by the previously used Cph1/EnvZ fusion protein ([http://partsregistry.org/Part:BBa_I15010 BBa_I15010]).
+We will be using one light input in the form of red light and two chemical inputs. The red light will be detected by the previously used Cph1/EnvZ fusion protein ([http://partsregistry.org/Part:BBa_I15010 BBa_I15010]).
-The blue light input will be derived from the ''Myxococcus xanthus'' carotenogenesis system, a list of relevant references can be found below.  In the event this input should prove difficult to implement, we will use a chemical input instead.
+The chemical inputs to be used are currently being determined.
-'''Blue-light References:'''
-# Moraleda-Muñoz A, Pérez J, Fontes M, Murillo FJ, Muñoz-Dorado J. (2005) ''Molecular Microbiology'' '''56''' (5):1159-68
+We have chosen to use light as an input for the reasons that it does not require altering the media, it can be turned on and off rapidly, and it has extremely high resolution and accuracy.
-# Browning DF, Whitworth DE, Hodgson DA. (2003) ''Molecular Microbiology'' '''48''' (1):237-251
-# Whitworth DE, Bryan SJ, Berry AE, McGowan SJ, Hodgson DA. (2004) ''Journal of Bacteriology'' '''186''' (23):7836-46
-# Whitworth DE, Hodgson DA. (2001) ''Molecular Microbiology'' '''42''' (3): 809-819
-# López-Rubio JJ, Elías-Arnanz M, Padmanabhan S, Murillo FJ. (2002) ''The Journal of Biological Chemistry'' '''277''' (9):7262-70
-We have chosen to use light as an input for many reasons: it does not require altering the media, it can be turned on and off rapidly, and it has extremely high resolution and accuracy.
 === The Logic Gates ===
-In order to have a functional adder, we are designing an AND gate as well as an XOR gate.
+CURRENTLY IN PROGRESS
 == Supporters ==

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