1. Abstruct

Concept & Model

A bacterial society designed in this project follows Pareto's principle as an Ant society does.

Requirements

Bistability
Coexistence by cell-cell communication.

Genetic circuit

Genetic circuit construction
new parts

GOAL

To confirm the behavior of the model - bistability of each individual and the system's stability under the coexsistence of the two types - in silico and in virto.

2. Works

Combinational Wet & Dry Approaches

0. Wet :　Hybrid promoter

1.Dry :　 Formulation

We wrote the Formulation

2.Wet : 　Assay

We decided the parameter of hill coefficients by the assay of AHL & IPTG

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3.Dry : 　Simulation

4.Wet : 　Assay

We tested whether our plasmids gave the other parameters to satisfy the simulation by the experiments using E. coli.

5.Future works

Continue this combinational approaches to sophisticate our model. See more.

3,About our team

Students
Satoru Akama | Kenichiro Iwasaki | Hiroki Kawahara | Hajime Nakatani

Advisors: Last year's member
Shotaro Ayukawa | Akio Kobayashi

Instructors
[http://www.sb.dis.titech.ac.jp/ Daisuke Kiga] | [http://www.es.dis.titech.ac.jp/ Masayuki Yamamura] | [http://nicosia.is.s.u-tokyo.ac.jp/~hagiya/ Masami Hagiya] | [http://www.sb.dis.titech.ac.jp/ Masahiko Uchiyama]

Links sunaba