McGill
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<u>'''Quorum-sensing coupled with the Repressilator'''</u> | <u>'''Quorum-sensing coupled with the Repressilator'''</u> | ||
| - | Our project is a continuation of one of the projects we presented last year: a two-gene oscillator | + | Our project is a continuation of one of the projects we presented last year: a two-gene oscillator with an 'On' and 'Off' switch using LacI and LuxI. This simple relaxation oscillator could be used as a modular component for the synchronization of other complex oscillating systems such as the repressilator. |
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| + | Quorum-sensing coupling between cells is achieved with a diffusible autoinducer AI (AHL) made from LuxI which promotes the synthesis of LacI from pLux. As Lac accumulates, it represses pLac which controls the synthesis of LuxI.<br> | ||
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[[McGill/Project Description|Project Description]]<br> | [[McGill/Project Description|Project Description]]<br> | ||
| - | [[McGill/ | + | [[McGill/Modeling and Simulations|Modeling and Simulations]]<br> |
| + | [[McGill/Team_2_More_Information|Animations]] <br> | ||
| + | [[McGill/Project Overview|Future Directions]]<br> | ||
| + | [[McGill/Parts|Parts/Biobricks]]<br> | ||
| + | [[McGill/Results|Results]]<br> | ||
| + | <br> | ||
| + | [[McGill/Project Evaluation|Project Evaluation]] <br> | ||
<center> | <center> | ||
| - | [[Image: | + | [[Image:2gene oscillator.jpg|320px]]<br> |
| - | + | </center><br> | |
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{| cellspacing="2px" cellpadding="20" border="0" style="padding: 0px; width: 750px | {| cellspacing="2px" cellpadding="20" border="0" style="padding: 0px; width: 750px | ||
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[[McGill/Lab Notebook|Lab Notebook]]<br> | [[McGill/Lab Notebook|Lab Notebook]]<br> | ||
[[McGill/Lab Protocols|Lab Protocols]]<br> | [[McGill/Lab Protocols|Lab Protocols]]<br> | ||
| - | [[McGill/ | + | [[McGill/Team_2_Background_Papers|Background Papers]] <br> |
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|width=240px style="padding: 5px| | |width=240px style="padding: 5px| | ||
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[[McGill/RI meetup|Rhode Island Meetup]]<br> | [[McGill/RI meetup|Rhode Island Meetup]]<br> | ||
[[McGill/urc|McGill Research Conference]]<br> | [[McGill/urc|McGill Research Conference]]<br> | ||
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| + | Please feel free to check out our work from last year at [https://2006.igem.org/wiki/index.php/McGill_University iGEM McGill 2006] | ||
Revision as of 19:05, 26 October 2007
Project OverviewQuorum-sensing coupled with the Repressilator Our project is a continuation of one of the projects we presented last year: a two-gene oscillator with an 'On' and 'Off' switch using LacI and LuxI. This simple relaxation oscillator could be used as a modular component for the synchronization of other complex oscillating systems such as the repressilator. Quorum-sensing coupling between cells is achieved with a diffusible autoinducer AI (AHL) made from LuxI which promotes the synthesis of LacI from pLux. As Lac accumulates, it represses pLac which controls the synthesis of LuxI.
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