Imperial

From 2007.igem.org

(Difference between revisions)
 
(66 intermediate revisions not shown)
Line 1: Line 1:
{{Template:IC07navmenu}}
{{Template:IC07navmenu}}
-
 
<html>
<html>
-
<link rel="stylesheet" href="/igem07/index.php?title=User:Alexander.wong/Stylesheets/mainpage.css&action=raw&ctype=text/css" type="text/css" />
+
<link rel="stylesheet" href="/igem07/index.php?title=User:Dirkvs/Stylesheets/mainpage.css&action=raw&ctype=text/css" type="text/css" />
<div id="wrap">
<div id="wrap">
<div id="maincontent">
<div id="maincontent">
-
 
-
<!-- Place Team Photo under here -->
 
-
<img src="http://openwetware.org/images/1/1a/IC07_teamphoto.jpg" width="610px" >
 
<!-- Start of Central Content Box -->
<!-- Start of Central Content Box -->
-
 
<div id="maincol">
<div id="maincol">
-
<table style="text-align: justify; background-color: #ffffff;"><tr>
+
 
-
  <td style="width: 50%; padding-right: 3px; vertical-align: top;">
+
 
-
<div id="SummaryBox">
+
<div id="OverviewBox">
-
<h2>Project Overview</h2>
+
<h2><b>Welcome!</b></h2>
-
<div class="parabox">Our contribution to the synthetic biology community this year will be the investigation of Cell-Free Chassis, the common platform on which Cell By Date and Infector Detector will be built.  
+
<div class="contentbox">The IC GEMs team consists of ten 2nd year undergraduates from Bioengineering and Bioscience. Our genuine collective interest in healthcare led to the targetting of <b>health and medicine related applications</b> this year. Together with the vision of an industry, the strategy we adopted for our projects is to use the Engineering Cycle to create reliable Synthetic Biology products where standards and quality control are strictly kept.
 +
 
                 </div>
                 </div>
         </div>
         </div>
-
  </td>
+
 
-
  <td style="width: 50%; padding-left: 3px; vertical-align: top;">
+
<div id="FeatureBox">
-
<div id="SummaryBox">
+
<div class="contentbox">
-
<h2>Our Achievements</h2>
+
<h1><b>Main Project</b> - <a href="https://2007.igem.org/Imperial/Infector_Detector/Introduction">Infector Detector</a></h1>  
 +
 
 +
Infector Detector is a system that will detect the presence of biofilm infections on urinary catheters by reporting on the presence of AHL, a signalling molecule used by E.<i>coli</i>, and output a fluorescent protein as a result. (<a href="https://2007.igem.org/Imperial/Infector_Detector/Introduction">more...</a>)
 +
<br><br>
 +
 
 +
<table style="background-color: #f5facf;" width="590px" align="center" border="0" cellpadding="7px" cellspacing="5">
 +
  <tr>
 +
      <td valign="top" style="text-align:justify;">
 +
          <center><img src="https://static.igem.org/mediawiki/2007/d/d5/IC07_IDnews.png" width="260px"></center>
 +
      </td>
 +
      <td>
 +
          <div id="SummaryBox">
 +
<h2>Main Achievements</h2>
<div class="parabox">
<div class="parabox">
                       <ul>
                       <ul>
-
                      <li>Investigated and characterised the in-vitro chassis
+
                       <li>Designed and modelled a device to <b>detect biofilms</b> and <b>prevent urinary catheter infections</b> like MRSA
-
                       <li>Designed and modelled a device to detect biofilms and potentially prevent diseases like MRSA
+
                      <li>Successfully utilized <b>cell-free chassis</b> for Infector Detector
-
                       <li>Characterised Infector Detector in terms of various AHL concentrations, at room temperature
+
                       <li>Characterised Infector Detector to <b>detect AHL at ambient temperatures</b>
-
                       <li>Designed and modelled a device to indicate spoilage of meat/break in the cold chain via the thermal history of the system
+
                       <li><a href="https://2007.igem.org/Imperial/Infector_Detector/F2620_Comparison"><b>Compared system expression</b></a> to <a href="http://partsregistry.org/Part:BBa_F2620">AHL Receiver (BBa_F2620)</a> transfer function.
-
                      <li>Characterised the pTet-GFP and pT7-GFP construct in-vitro
+
                       </ul>
                       </ul>
-
 
                 </div>
                 </div>
         </div>
         </div>
-
  </td>
 
-
</tr></table>
 
-
<div id="FeatureBox">
 
-
<div class="contentbox">
 
-
<h2>Main Project - <a href="...">Infector Detector</a></h2> Infector Detector is a system that will detect the presence of biofilm infections on urinary catheters by reporting on the presence of AHL, a signalling molecule used by E.<i>coli</i>, and output a fluorescent protein as a result. (<a href="...">more...</a>)<br>
 
-
<br>
 
-
<table width="550px" align="center" border="0" cellspacing="0">
 
-
  <tr>
 
-
      <td align="center" style="background-color: #f5facf;"><img src="https://static.igem.org/mediawiki/2007/d/d7/Icgems-Devcycle-uprightarrow.png" width="70px"><br>
 
-
      </td>
 
-
      <td align="right" valign="top" style="text-align: center; background-color: #ffffff;">Image for Specs.<br>SPECIFICATIONS
 
-
      </td>
 
-
      <td align="center" style="background-color: #f5facf;"><img src="https://static.igem.org/mediawiki/2007/7/70/Icgems-Devcycle-rightdownarrow.png" width="70px"><br>
 
-
      </td>
 
-
  </tr>
 
-
  <tr>
 
-
      <td style="text-align: center; background-color: #ffffff;">Image for Testing/Validation.<br>TESTING / VALIDATION
 
-
      </td>
 
-
      <td style="text-align: center; background-color: #ffffff;">Image for full system.<br>
 
-
      </td>
 
-
      <td style="text-align: center; background-color: #ffffff;">Image for Design.<br>DESIGN
 
-
      </td>
 
-
  </tr>
 
-
  <tr>
 
-
      <td align="center" style="background-color: #f5facf;"><img src="https://static.igem.org/mediawiki/2007/e/e0/Icgems-Devcycle-uparrow.png" height="80px"><br>
 
-
      </td>
 
-
      <td style="text-align: center; background-color: #ffffff;">Image for full system.<br>INFECTOR DETECTOR
 
-
      </td>
 
-
      <td align="center" style="background-color: #f5facf;"><img src="https://static.igem.org/mediawiki/2007/d/d1/Icegems-Devcycle-downarrow.png" height="80px"><br>
 
-
      </td>
 
-
  </tr>
 
-
  <tr>
 
-
      <td style="text-align: center; background-color: #ffffff;">Image for Implementation.<br>IMPLEMENTATION
 
-
      </td>
 
-
      <td style="text-align: center; background-color: #f5facf;"><img src="https://static.igem.org/mediawiki/2007/4/49/Icgems-Devcycle-leftarrow.png" width="80px"><br>
 
-
      </td>
 
-
      <td style="text-align: center; background-color: #ffffff;">Image for Modelling.<br>MODELLING
 
       </td>
       </td>
   </tr>
   </tr>
Line 77: Line 46:
</div>
</div>
 +
</div> 
 +
 +
 +
<div id="TechnoBox">
 +
<div class="contentbox">
 +
<h2><b>Foundational technology</b> - <a href="https://2007.igem.org/Imperial/Cell-Free/Whatis">Cell-Free Systems</a></h2>
 +
<br>
 +
<center><img src="https://static.igem.org/mediawiki/2007/b/bb/IC07_CFS_components.png" width="400px"></center>
 +
<table style="background-color: #dff7d6;" width="560px" align="center" border="0" cellpadding="7px" cellspacing="5">
 +
      <td valign="top" style="text-align:justify;">Power your iGEM projects with Cell-Free Systems! Find out what this new chassis has done for us, and what it can do for you! (<a href="https://2007.igem.org/Imperial/Cell-Free/Whatis">more...</a>)<br>
 +
 +
</table>
 +
                </div>
</div>   
</div>   
Line 82: Line 64:
<div id="FeatureBox">
<div id="FeatureBox">
<div class="contentbox">
<div class="contentbox">
-
<h2>Sub Project - <a href="...">Cell by Date</a></h2> Cell by Date will report when beef has been out of the fridge for too long. It produces fluorescent proteins at ambient temperatures above 8&deg;C. (<a href="...">more...</a>)<br>
+
<h1><b>Sub Project</b> - <a href="https://2007.igem.org/Imperial/Cell_by_Date/Introduction">Cell by Date</a></h1>  
 +
Cell by Date will report when ground beef has been out of the cold chain for too long. It produces fluorescent proteins at ambient temperatures above 8&deg;C. (<a href="https://2007.igem.org/Imperial/Cell_by_Date/Introduction">more...</a>)<br>
 +
<table style="background-color: #f5facf;" width="560px" align="center" border="0" cellpadding="7px" cellspacing="5">
 +
  <tr>
 +
      <td valign="center"><img src="https://static.igem.org/mediawiki/2007/7/74/CBDCartoonfront.png" width="220px">
 +
 +
      <td valign="top" style="text-align:left;">
 +
          <div id="SummaryBox" style="width: 300px;">
 +
<h2>Main Achievements</h2>
 +
<div class="parabox" style="width: 270px;">
 +
                      <ul>
 +
                      <li>Designed and modelled a device to <b>indicate spoilage of meat</b>/break in the cold chain via the <b>thermal history</b> of the system
 +
                      <li> Utilised project results to <b>characterise cell-free chassis</b>
 +
                      <li> Characterised <a href="http://partsregistry.org/Part:BBa_I13522">pTet-GFP</a> and <a href="http://partsregistry.org/Part:BBa_I719015">pT7-GFP</a> under <b>isothermal conditions</b>
 +
                      </ul>
 +
                </div>
 +
        </div>
 +
      </td>
 +
  </tr>
 +
</table>
</div>
</div>
</div>   
</div>   
Line 117: Line 118:
<div class="post-it greenbox">
<div class="post-it greenbox">
-
<h2><b><a href="" title="">Meet the Team</a></b></h2>
+
<h2><b><a href="https://2007.igem.org/Imperial/Team" title="">Meet the Team</a></b></h2>
 +
<br />
 +
<img src="https://static.igem.org/mediawiki/2007/9/97/IC07_teamphoto3.jpg" width="230px">
 +
<br>
 +
</div>
-
                    <table style="background-color: #dff7d6; filter:alpha(opacity=80); -moz-opacity:0.8; font-size: .95em;">
+
<div class="post-it bluebox">
-
                      <tr style="font-weight: bold;">
+
<h2><b> <a href="https://2007.igem.org/Imperial/Open_Science_on_OpenWetWare" title="">Open Science on OpenWetWare</a></b></h2>
-
                          <td>Undergraduates</td>
+
  <table style="background-color: #d9f0f8; filter:alpha(opacity=80); -moz-opacity:0.8; font-size: .95em;">
-
                          <td style="text-align: right; padding-left: 5px;">Faculty Advisors</td>
+
        <tr style="font-weight: bold;">
-
                      </tr>
+
              <td>We did Open Science!</td>
-
                      <tr>
+
        </tr><tr>
-
                          <td>James Chappell</td>
+
              <td>
-
                          <td style="text-align: right; padding-left: 5px;">Prof Paul Freemont</td>
+
              Our projects were run and organised using OWW, with updates on a day-to-day basis! Click <a href="https://2007.igem.org/Imperial/Open_Science_on_OpenWetWare" title="">here to access our <b>400+ pages of full documentation!</b></a>
-
                      </tr>
+
              </td></tr>
-
                      <tr>
+
  </table>
-
                          <td>Lucas Hadjilucas</td>
+
</div>
-
                          <td style="text-align: right; padding-left: 5px;">Prof Richard Kitney</td>
+
-
                      </tr>
+
-
                      <tr>
+
-
                          <td>Jaroslaw Karcz</td>
+
-
                          <td style="text-align: right; padding-left: 5px;"></td>
+
-
                      </tr>
+
-
                      <tr>
+
-
                          <td>Anthony Lazzaro</td>
+
-
                          <td style="text-align: right; font-weight:bold; padding-left: 5px;">Supervisors</td>
+
-
                      </tr>
+
-
                      <tr>
+
-
                          <td>Peixuan Pey</td>
+
-
                          <td style="text-align: right; padding-left: 5px;">Vincent Rouilly</td>
+
-
                      </tr>
+
-
                      <tr>
+
-
                          <td>Maira Tariq</td>
+
-
                          <td style="text-align: right; padding-left: 5px;">Matthieu Bultelle</td>
+
-
                      </tr>
+
-
                      <tr>
+
-
                          <td>Ben Yi Tew</td>
+
-
                          <td style="text-align: right; padding-left: 5px;">Kirsten Jensen</td>
+
-
                      </tr>
+
-
                      <tr>
+
-
                          <td>Cheuk Ka Tong</td>
+
-
                          <td style="text-align: right; padding-left: 5px;">Dr. Duo Lu</td>
+
-
                      </tr>
+
-
                      <tr>
+
-
                          <td>Dirk van Swaay</td>
+
-
                          <td style="text-align: right; padding-left: 5px;"></td>
+
-
                      </tr>
+
-
                      <tr>
+
-
                          <td>Alexander Wong</td>
+
-
                          <td></td>
+
-
                      </tr>
+
-
                    </table>
+
 +
<div class="post-it pinkbox">
 +
<h2><b>Contributions to Registry</b></h2>
 +
  <table style="background-color: #f0dbcc; filter:alpha(opacity=80); -moz-opacity:0.8; font-size: .95em;">
 +
        <tr style="font-weight: bold;">
 +
              <td>Chassis Additions</td>
 +
        </tr><tr>
 +
              <td>
 +
              <a href="http://partsregistry.org/Chassis/Cell-Free_Systems">Cell-Free Systems</a><br>
 +
              <a href="http://partsregistry.org/Chassis/Cell-Free_Systems/Homemade_E.coli_S30">- Homemade <i>E. coli</i> S30</a><br>
 +
          <a href="http://partsregistry.org/Chassis/Cell-Free_Systems/Commercial_E.coli_S30">- Commercial <i>E. coli</i> S30</a><br>
 +
              <a href="http://partsregistry.org/Chassis/Cell-Free_Systems/Commercial_E.coli_T7_S30">- Commercial <i>E. coli</i> T7 S30</a><br>
 +
              <a href="http://partsregistry.org/Chassis/Cell-Free_Systems/Vesicle">- Vesicle Encapsulation</a><br>
 +
              </td></tr>
 +
        <tr style="font-weight: bold;">
 +
              <td>Part/Construct Additions</td>
 +
        </tr><tr>
 +
              <td>
 +
              <a href="http://partsregistry.org/Part:BBa_I719005">T7 promoter (BBa_I719005)</a><br>
 +
              <a href="http://partsregistry.org/Part:BBa_I719015">pT7 with GFP reporter (BBa_I719015)</a>
 +
              </td></tr>
 +
        <tr style="font-weight: bold;">
 +
              <td>Part/Construct Characterisation</td>
 +
        </tr><tr>
 +
              <td>
 +
              <a href="http://partsregistry.org/Part:BBa_F2620"> AHL Receiver (BBa_F2620)</a> <br>
 +
              <a href="http://partsregistry.org/Part:BBa_I13522">pTet GFP (BBa_I13522)</a><br>
 +
              <a href="http://partsregistry.org/Part:BBa_J37032">pLux GFP (BBa_J37032)</a><br>
 +
              </td>
 +
        </tr>
 +
  </table>
</div>
</div>
-
+
 
<div class="post-it yellowbox">
<div class="post-it yellowbox">
-
<h2><b><a href="" title="">Fun with iGEM</a></b></h2>
+
<h2><b><a href="https://2007.igem.org/Imperial/Fun" title="">Fun with iGEM</a></b></h2>
 +
  <table style="background-color: #f7fbd7; filter:alpha(opacity=80); -moz-opacity:0.8; font-size: .95em;">
 +
      <td> Pictures, Quotes and More!
 +
  </table>
 +
 
</div>
</div>
-
+
 
<div class="post-it whitebox" style="filter:alpha(opacity=80); -moz-opacity:0.8;">
<div class="post-it whitebox" style="filter:alpha(opacity=80); -moz-opacity:0.8;">
-
<h2><b><a href="" title="">Acknowledgements</a></b></h2>
+
<h2><b><a href="https://2007.igem.org/Imperial/Acknowledgements" title="">Acknowledgements</a></b></h2>
   <table style="background-color: #eeeeee; filter:alpha(opacity=80); -moz-opacity:0.8; font-size: .95em;">
   <table style="background-color: #eeeeee; filter:alpha(opacity=80); -moz-opacity:0.8; font-size: .95em;">
               <td>
               <td>
Line 180: Line 184:
               IC Faculty of Engineering<br>
               IC Faculty of Engineering<br>
               IC Faculty of Natural Sciences<br>
               IC Faculty of Natural Sciences<br>
-
               European Commission, Synbiocomm Project<br><br>
+
               European Commission, Synbiocomm Project<br>
-
              <a href="http://www.geneart.com"><img src="http://www.geneart.com/fileadmin/templates/img/logo.gif" width="180"></a>
+
               </td>
               </td>
   </table>
   </table>
Line 192: Line 195:
</div>
</div>
 +
 +
<!-- DO NOT REMOVE : Start of StatCounter Code -->
 +
<script type="text/javascript">
 +
var sc_project=3073879;
 +
var sc_invisible=0;
 +
var sc_partition=33;
 +
var sc_security="e7bc3456";
 +
</script>
 +
 +
<script type="text/javascript" src="http://www.statcounter.com/counter/counter_xhtml.js"></script><noscript><div class="statcounter"><a class="statcounter" href="http://www.statcounter.com/"><img class="statcounter" src="http://c34.statcounter.com/3073879/0/e7bc3456/0/" alt="blog counter" /></a></div></noscript>
 +
<!-- DO NOT REMOVE : End of StatCounter Code -->
 +
</html>
</html>

Latest revision as of 03:34, 27 October 2007

Welcome!

The IC GEMs team consists of ten 2nd year undergraduates from Bioengineering and Bioscience. Our genuine collective interest in healthcare led to the targetting of health and medicine related applications this year. Together with the vision of an industry, the strategy we adopted for our projects is to use the Engineering Cycle to create reliable Synthetic Biology products where standards and quality control are strictly kept.

Main Project - Infector Detector

Infector Detector is a system that will detect the presence of biofilm infections on urinary catheters by reporting on the presence of AHL, a signalling molecule used by E.coli, and output a fluorescent protein as a result. (more...)

Main Achievements

  • Designed and modelled a device to detect biofilms and prevent urinary catheter infections like MRSA
  • Successfully utilized cell-free chassis for Infector Detector
  • Characterised Infector Detector to detect AHL at ambient temperatures
  • Compared system expression to AHL Receiver (BBa_F2620) transfer function.

Foundational technology - Cell-Free Systems


Power your iGEM projects with Cell-Free Systems! Find out what this new chassis has done for us, and what it can do for you! (more...)

Sub Project - Cell by Date

Cell by Date will report when ground beef has been out of the cold chain for too long. It produces fluorescent proteins at ambient temperatures above 8°C. (more...)

Main Achievements

  • Designed and modelled a device to indicate spoilage of meat/break in the cold chain via the thermal history of the system
  • Utilised project results to characterise cell-free chassis
  • Characterised pTet-GFP and pT7-GFP under isothermal conditions

Retrieved from "http://2007.igem.org/wiki/index.php/Imperial"