USTC/RepressionMatrixFromLiterature
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| - | [[Image:USTC_MullerRepression. | + | The Repression Matrix comes from other's previous work results[[USTC/RepressionMatrixFromLiterature#References|[1,2,3]]]. However, we hardly get an 'ORM' because the cross repression are obvious according to this results. i.e. we may not obtain stable Repressor-Promoter Pairs as our wires with high fidelity. |
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| + | [[Image:USTC_MullerRepression.png|thumb|center|800px|'''Figure I''' The same with the former RM that red color represents a high repression while blue represent reverse. This Matrix are not directly from literatures but from the data by previous research work.]] | ||
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| + | == References == | ||
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| + | 1. Lehming, N.; Sartorius, J.; Niemöller, M.; Genenger, G.; v Wilcken-Bergmann, B. & Müller-Hill, B. (1987), 'The interaction of the recognition helix of lac repressor with lac operator.', <i>EMBO J</i> 6(10), 3145--3153. | ||
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| + | 2. Lehming, N.; Sartorius, J.; Oehler, S.; von Wilcken-Bergmann, B. & Müller-Hill, B. Recognition helices of lac and lambda repressor are oriented in opposite directions and recognize similar DNA sequences. <i>PNAS</i>, 1988, 85, 7947-7951 | ||
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| + | 3. Sartorius, J.; Lehming, N.; Kisters, B.; von Wilcken-Bergmann, B. & Müller-Hill, B. (1989), 'lac repressor mutants with double or triple exchanges in the recognition helix bind specifically to lac operator variants with multiple exchanges.', <i>EMBO J</i> 8(4), 1265--1270. | ||
Latest revision as of 16:27, 25 October 2007
The Repression Matrix comes from other's previous work results[1,2,3]. However, we hardly get an 'ORM' because the cross repression are obvious according to this results. i.e. we may not obtain stable Repressor-Promoter Pairs as our wires with high fidelity.
References
1. Lehming, N.; Sartorius, J.; Niemöller, M.; Genenger, G.; v Wilcken-Bergmann, B. & Müller-Hill, B. (1987), 'The interaction of the recognition helix of lac repressor with lac operator.', EMBO J 6(10), 3145--3153.
2. Lehming, N.; Sartorius, J.; Oehler, S.; von Wilcken-Bergmann, B. & Müller-Hill, B. Recognition helices of lac and lambda repressor are oriented in opposite directions and recognize similar DNA sequences. PNAS, 1988, 85, 7947-7951
3. Sartorius, J.; Lehming, N.; Kisters, B.; von Wilcken-Bergmann, B. & Müller-Hill, B. (1989), 'lac repressor mutants with double or triple exchanges in the recognition helix bind specifically to lac operator variants with multiple exchanges.', EMBO J 8(4), 1265--1270.
