PennState/Lab/Notebooks

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<td class="tdheadR"><b>Project Modules</b></td>
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<h3>Our Lab Notebooks</h3></td>
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<h3>Our Lab Notebooks</h3></td>
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<td class="tdboxes"><a href="https://2007.igem.org/BerkiGEM2007Present1"><img border="0" src="https://static.igem.org/mediawiki/2007/e/e5/Berk-Icon-Oxygen.png" width="121" height="121"></a></td>
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<td class="tdboxes"><a href="http://openwetware.org/wiki/IGEM:PennState/Labbook/GalenLynch"><img border="0" src="https://static.igem.org/mediawiki/2007/e/ef/PennStateiGEM2007Galen.jpg" width="130" height="150"></a></td>
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<td class="tddesc"><b><a href="https://2007.igem.org/BerkiGEM2007Present1">Oxygen Transport</a></b><p><i>Our system is
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<td class="tddesc"><b><a href="http://openwetware.org/wiki/IGEM:PennState/Labbook/GalenLynch"> Galen's Lab Notebook</a></b><p></td>
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designed to produce Hemoglobin, Heme, and the necessary
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chaperones and detoxifying agents to promote the transport
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of oxygen throughout the bloodstream.&nbsp; We also
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investigated alternates to hemoglobin and other strategies
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<a href="http://openwetware.org/wiki/IGEM:PennState/Labbook/GarrettTobin"><img border="0" src="https://static.igem.org/mediawiki/2007/thumb/9/92/PennStateiGEM2007Garrett.jpg/500px-PennStateiGEM2007Garrett.jpg" width="130" height="150"></a></td>
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for its production.</i></td>
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<td class="tddesc"><b><a href="http://openwetware.org/wiki/IGEM:PennState/Labbook/GarrettTobin"> Garrett's Lab Notebook</a></b><p></td>
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<a href="https://2007.igem.org/BerkiGEM2007Present4"><img border="0" src="https://static.igem.org/mediawiki/2007/b/ba/Berk-Icon-Chassis.png" width="121" height="121"></a></td>
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<a href="http://openwetware.org/wiki/IGEM:PennState/Labbook/LucienWeiss"><img border="0" src="https://static.igem.org/mediawiki/2007/0/00/PennStateiGEM2007Luc.jpg" width="130" height="150"></a></td>
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<td class="tddesc"><b><a href="https://2007.igem.org/BerkiGEM2007Present4">The Chassis</a></b><p><i>Our bacterial
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<td class="tddesc"><b><a href="http://openwetware.org/wiki/IGEM:PennState/Labbook/LucienWeiss"> Luc's Lab Notebook</a></b><p></td>
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chassis has been heavily modified to remove its
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sepsis-inducing toxicity, immunogenic factors, and ability to grow
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within the bloodstream, as well as promote its ability to last
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longer in the bloodstream by masking it from the immune
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<a href="http://openwetware.org/wiki/IGEM:PennState/Labbook/NoahJohnson"><img border="0" src="https://static.igem.org/mediawiki/2007/thumb/d/dc/PennStateiGEM2007Noah.jpg/500px-PennStateiGEM2007Noah.jpg" width="130" height="150"></a></td>
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system.</i></td>
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<td class="tddesc"><b><a href="http://openwetware.org/wiki/IGEM:PennState/Labbook/NoahJohnson"> Noah's Lab Notebook</a></b><p></td>
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<a href="https://2007.igem.org/BerkiGEM2007Present3"><img border="0" src="https://static.igem.org/mediawiki/2007/8/8d/Berk-Icon-Controller.png" width="121" height="121"></a></td>
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<td class="tddesc"><b><a href="https://2007.igem.org/BerkiGEM2007Present3">The Controller</a></b><p><i>The Controller
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is an integrated genetic circuit comprised of two plasmids that allows
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stable maintenance of the system's various operons on a large single-copy
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plasmid in a dormant state.  Upon induction, the copy number of the
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operons and their transcription increase 100-fold resulting in a
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dramatic increase in protein expression.</i></td>
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<a href="https://2007.igem.org/BerkiGEM2007Present5"><img border="0" src="https://static.igem.org/mediawiki/2007/thumb/d/dc/PennStateiGEM2007Noah.jpg/500px-PennStateiGEM2007Noah.jpg" width="121" height="121"></a></td>
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<td class="tddesc"><b><a href="https://2007.igem.org/BerkiGEM2007Present5">Genetic Self-Destruct</a></b><p><i>To
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prevent chance of infection or unwanted proliferation after
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hemoglobin production, we have engineered a genetic
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self-destruct mechanism whereby when induced, the bacterial
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cell will express a genetic material-degrading toxin which
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kills the cell, but leaves it physically intact.</i></td>
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<a href="https://2007.igem.org/BerkiGEM2007Present2"><img border="0" src="https://static.igem.org/mediawiki/2007/c/ce/Berk-Icon-Freeze-Drying.png" width="121" height="121"></a></td>
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<td class="tddesc"><b><a href="https://2007.igem.org/BerkiGEM2007Present2">Freeze Drying</a></b><p><i>To
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enable preservation of our bacteria for prolonged periods,
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we are including the ability to produce the compounds
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hydroxyectoine and trehalose that will enable our bacteria to
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survive freeze-drying intact.&nbsp; This will dramatically
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increase shelf-life and decrease transport costs.</i></td>
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Latest revision as of 19:37, 26 October 2007

Our Lab Notebooks
Galen's Lab Notebook
Garrett's Lab Notebook
Luc's Lab Notebook
Noah's Lab Notebook

Retrieved from "http://2007.igem.org/wiki/index.php/PennState/Lab/Notebooks"