ETHZ/Simulations
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== Basic Model == | == Basic Model == | ||
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+ | ==== Constitutively produced proteins ==== | ||
[[Image:Model01.png]] | [[Image:Model01.png]] | ||
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+ | ==== Learning system ==== | ||
[[Image:Model02.png]] | [[Image:Model02.png]] | ||
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+ | ==== Reporter system ==== | ||
[[Image:Model03.png]] | [[Image:Model03.png]] |
Revision as of 10:03, 15 August 2007
Contents |
Basic Model
Constitutively produced proteins
Learning system
Reporter system
System Equations
Model Parameters
Parameter | Value | Description |
---|---|---|
aR | basic production of lacI | |
aS | basic production of tetR | |
aL | basic production of luxR | |
aQ1 | basic production of cI | |
aQ2 | basic production of p22cII | |
aGFP | basic production of GFP | |
aRFP | basic production of RFP | |
dR | degradation of lacI | |
dS | degradation of tetR | |
dL | degradation of luxR | |
dQ1 | degradation of cI | |
dQ2 | degradation of p22cII | |
dGFP | degradation of GFP | |
dRFP | degradation of RFP | |
kR | 0.22 [mM/h] | promoter strength (Promoter R0010) |
kS | promoter strength (Promoter R0040) | |
kL | promoter strength (Promoter R0062) | |
kQ1 | 0.20 [mM/h] | promoter strength (Promoter R0051) |
kQ2 | promoter strength (Promoter R0053) | |
KR | 2e-3 [mM/h] | lacI repressor dissociation constant |
KIR | 1.5e-10 [mM/h] | IPTG-lacI repressor dissociation constant |
KS | tetR repressor dissociation constant | |
KIS | aTc-tetR repressor dissociation constant | |
KL | luxR activator dissociation constant | |
KIL | AHL-luxR activator dissociation constant | |
KQ1 | 2e-3 [mM/h] | cI repressor dissociation constant |
KQ2 | p22cII repressor dissociation constant | |
nR | 1 | lacI repressor Hill cooperativity |
nIR | 2 | IPTG-lacI repressor Hill cooperativity |
nS | tetR repressor Hill cooperativity | |
nIS | aTc-tetR repressor Hill cooperativity | |
nL | luxR activator Hill cooperativity | |
nIL | AHL-luxR activator Hill cooperativity | |
nQ1 | 1.9 | cI repressor Hill cooperativity |
nQ2 | p22cII repressor Hill cooperativity |
Variable Mapping
Variable | Compound |
---|---|
R | lacI |
IR | IPTG |
S | tetR |
IS | aTc |
L | luxR |
IL | AHL |
Q1 | cI |
Q2 | p22cII |