Waterloo
From 2007.igem.org
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| colspan="4" style="padding:5px; font-size:large" | Abstract | | colspan="4" style="padding:5px; font-size:large" | Abstract | ||
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| - | | colspan="2" style="vertical-align:top; border-bottom-width:thin; border-bottom-color:black; border-bottom-style:solid; padding:5px" |- goals | + | | colspan="2" style="vertical-align:top; border-bottom-width:thin; border-bottom-color:black; border-bottom-style:solid; padding:5px" | The goal of this project is to design a basic device for computing. Our idea was to reproduce a circuit element called a half adder with DNA, which takes in two 1-bit inputs, adds them, and outputs a sum and a carry. Our device responds to two inputs: red light and the chemical tetracycline. The input sensors control a set of genetic switches in order to carry out the computation and fluoresces green and/or red depending on the outcome. |
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| + | - goals | ||
- biological implementation of a fundamental engineering concept, the half-adder | - biological implementation of a fundamental engineering concept, the half-adder | ||
- half adder calculates the sum of two 1-bit inputs | - half adder calculates the sum of two 1-bit inputs | ||
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- input sensors control genetic switches in order to carry out logic functions | - input sensors control genetic switches in order to carry out logic functions | ||
- output of the half-adder function...green or red fluorescence | - output of the half-adder function...green or red fluorescence | ||
| + | - applications | ||
| + | - why is it important? | ||
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| colspan="2" style="border-bottom-width:thin; border-bottom-color:black; border-bottom-style:solid; padding:5px; vertical-align:middle" | [[Image:Design schematic.jpg|center|400px|Schematic Design of Biological Half-Adder]] | | colspan="2" style="border-bottom-width:thin; border-bottom-color:black; border-bottom-style:solid; padding:5px; vertical-align:middle" | [[Image:Design schematic.jpg|center|400px|Schematic Design of Biological Half-Adder]] | ||
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Revision as of 19:04, 26 October 2007
| Our Team |
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| The UW iGEM team is a very interdisciplinary group. Our team members span three faculties: Science, Mathematics, and Engineering, and represent a wide range of undergraduate programs: Biology, Biomedical Sciences, Biochemistry, Computer Science, Bioinformatics, Computer Engineering, Electrical Engineering, Chemical Engineering, and Mathematical Physics.
Drawing on our diverse backgrounds, we bring a wide range of skills and modes of creative thinking to our iGEM project. The iGEM competition is providing us with an opportunity to become more familiar with the emerging field of synthetic biology in an engaging and fun atmosphere. In addition to gaining experience in the design, construction, and analysis of genetic circuits, we are also meeting the challenge of bringing together a large, diverse group toward a common goal. |
| Our Project | |||
| Abstract | |||
| The goal of this project is to design a basic device for computing. Our idea was to reproduce a circuit element called a half adder with DNA, which takes in two 1-bit inputs, adds them, and outputs a sum and a carry. Our device responds to two inputs: red light and the chemical tetracycline. The input sensors control a set of genetic switches in order to carry out the computation and fluoresces green and/or red depending on the outcome.
- goals - biological implementation of a fundamental engineering concept, the half-adder - half adder calculates the sum of two 1-bit inputs project - bacterial sensor which responds to two inputs: red light and the chemical tetracycline - input sensors control genetic switches in order to carry out logic functions - output of the half-adder function...green or red fluorescence - applications - why is it important? |  | ||
| Project Design | Mathematical Modelling | Construction and Testing | Future Work |
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//Modelling |
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| Acknowledgements | ||||||||||||||
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| [http://www.science.uwaterloo.ca/fsf/index.html Faculty of Science Foundation ] | [http://www.student.math.uwaterloo.ca/~mefcom/ Mathematics Endowment Fund ] | [http://www.eng.uwaterloo.ca/~sff/ Sir Sanford Fleming Foundation] | [http://www.weef.uwaterloo.ca/ Waterloo Engineering Endowment Fund] | [http://www.science.uwaterloo.ca/~watsef/mainpage.html Waterloo Science Endowment Fund] | ||||||||||
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| [http://www.engineering.uwaterloo.ca University of Waterloo Faculty of Engineering] | [http://www.science.uwaterloo.ca University of Waterloo Faculty of Science] | [http://www.math.uwaterloo.ca University of Waterloo Faculty of Mathematics] | ||||||||||||
We would like to thank the following people for their support and guidance:
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