Bay Area RSI
From 2007.igem.org
Amendelsohn (Talk | contribs) |
Amendelsohn (Talk | contribs) |
||
| Line 1: | Line 1: | ||
'''Bay Area RSI Team''' | '''Bay Area RSI Team''' | ||
| - | Our team consists of students from University of California at Berkeley and Stanford University. Our goal is to repair damaged hearts. We are engineering embryonic stem-like cells to recognize and bind to damaged heart | + | Our team consists of students from University of California at Berkeley and Stanford University. Our goal is to repair damaged hearts. We are engineering embryonic stem-like cells to autonomously differentiate into cardiomyocytes, recognize and bind to damaged heart cells and then activate a defined program. Bound cells will express anti-apoptosis and anti-necrosis proteins to prevent cell death, express increased amounts of a cell-cell adhesion molecule to stimulate the formation of a sheet of cells and to cause some of the cells to penetrate into the inner layers of the heart. Cells will also express a growth factor to stimulate new blood vessel formation. Cells that fail to bind in a defined amount of time are programmed to self-destruct. |
| - | |||
| - | |||
== Repairing Infarcted Hearts == | == Repairing Infarcted Hearts == | ||
| Line 17: | Line 15: | ||
[[Activation of Stem Cell Effectors]] | [[Activation of Stem Cell Effectors]] | ||
| + | |||
| + | == Our Assembly Methods == | ||
| + | [[ Rapid Assembly of Complex Parts ]] | ||
| + | |||
| + | == About Our Team == | ||
| + | |||
| + | [[ Regenerative Sciences Institute and the Bay Area RSI Team ]] | ||
| + | |||
| + | |||
| + | For more information, please visit our private wiki. | ||
| + | Our private wiki is available at [http://www.regensci.org/cgi-bin/twiki/view/IGEM2007/WebHome RSI Bay Area Team Wiki] | ||
| + | Sections of our wiki that contain copyrighted journal articles are not public. However, we are in the process of adding public pages that do not have copyright problems. | ||
Revision as of 21:40, 26 October 2007
Bay Area RSI Team
Our team consists of students from University of California at Berkeley and Stanford University. Our goal is to repair damaged hearts. We are engineering embryonic stem-like cells to autonomously differentiate into cardiomyocytes, recognize and bind to damaged heart cells and then activate a defined program. Bound cells will express anti-apoptosis and anti-necrosis proteins to prevent cell death, express increased amounts of a cell-cell adhesion molecule to stimulate the formation of a sheet of cells and to cause some of the cells to penetrate into the inner layers of the heart. Cells will also express a growth factor to stimulate new blood vessel formation. Cells that fail to bind in a defined amount of time are programmed to self-destruct.
Repairing Infarcted Hearts
Timed Stem Cell Self-Destruction
Activation of Stem Cell Effectors
Our Assembly Methods
Rapid Assembly of Complex Parts
About Our Team
Regenerative Sciences Institute and the Bay Area RSI Team
For more information, please visit our private wiki.
Our private wiki is available at [http://www.regensci.org/cgi-bin/twiki/view/IGEM2007/WebHome RSI Bay Area Team Wiki]
Sections of our wiki that contain copyrighted journal articles are not public. However, we are in the process of adding public pages that do not have copyright problems.
