McGill

From 2007.igem.org

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(Project Overview)
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== Project Overview ==
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<u>'''Quorum-sensing coupled with the Repressilator'''</u>
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Our project is a continuation of one of the projects we presented last year: a two-gene oscillator with an 'On' and 'Off' switch using LacI and LuxI. This simple relaxation oscillator could be used as a modular component for the synchronization of other complex oscillating systems such as the repressilator. 
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Quorum-sensing coupling between cells is achieved with a diffusible autoinducer AI (AHL) made from LuxI which promotes the synthesis of LacI from pLux. As Lac accumulates, it represses pLac which controls the synthesis of LuxI.<br>
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[[McGill/Project Description|Project Description]]<br>
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[[McGill/Modeling and Simulations|Modeling and Simulations]]<br>
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[[McGill/Team_2_More_Information|Animations]] <br>
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[[McGill/Project Overview|Future Directions]]<br>
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[[McGill/Parts|Parts/Biobricks]]<br>
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[[McGill/Results|Results]]<br>
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<li><a href="https://2007.igem.org/McGill/Project_Description">Project Description</a></li>
<li><a href="https://2007.igem.org/McGill/Project_Description">Project Description</a></li>
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== Project Overview ==
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<u>'''Quorum-sensing coupled with the Repressilator'''</u>
 +
 +
Our project is a continuation of one of the projects we presented last year: a two-gene oscillator with an 'On' and 'Off' switch using LacI and LuxI. This simple relaxation oscillator could be used as a modular component for the synchronization of other complex oscillating systems such as the repressilator. 
 +
 +
Quorum-sensing coupling between cells is achieved with a diffusible autoinducer AI (AHL) made from LuxI which promotes the synthesis of LacI from pLux. As Lac accumulates, it represses pLac which controls the synthesis of LuxI.<br>
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<center>
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[[Image:2gene oscillator.jpg|320px]]<br>
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</center><br>
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<br>
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[[McGill/Project Description|Project Description]]<br>
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[[McGill/Modeling and Simulations|Modeling and Simulations]]<br>
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[[McGill/Team_2_More_Information|Animations]] <br>
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[[McGill/Project Overview|Future Directions]]<br>
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[[McGill/Parts|Parts/Biobricks]]<br>
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[[McGill/Results|Results]]<br>
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<br>
<br>
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Revision as of 00:15, 27 October 2007

Banner 1.gif

The official wiki of the McGill University iGEM 2007 team of Montreal, Quebec, Canada

McGillIgem2007team.jpg



Contents

Project Overview

Quorum-sensing coupled with the Repressilator

Our project is a continuation of one of the projects we presented last year: a two-gene oscillator with an 'On' and 'Off' switch using LacI and LuxI. This simple relaxation oscillator could be used as a modular component for the synchronization of other complex oscillating systems such as the repressilator.

Quorum-sensing coupling between cells is achieved with a diffusible autoinducer AI (AHL) made from LuxI which promotes the synthesis of LacI from pLux. As Lac accumulates, it represses pLac which controls the synthesis of LuxI.

2gene oscillator.jpg



Project Description
Modeling and Simulations
Animations
Future Directions
Parts/Biobricks
Results


Bacteria1.jpg In the Lab

Lab Notebook
Lab Protocols
Background Papers


Greenbulb.jpg The Team

Team Members
Mailing List

Sine.jpg Pictures

[http://www.flickr.com/photos/cumbers/archives/date-posted/2007/08/21/ Brown University Meetup] (External)
Rhode Island Meetup
McGill Research Conference

Please feel free to check out our work from last year at iGEM McGill 2006