BerkiGEM2007 WikiPlaying3
From 2007.igem.org
(Difference between revisions)
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<p class="style28"><span class="style25"><a href="https://2007.igem.org/Berkeley_UC_Introduction">Introduction</a><br> | <p class="style28"><span class="style25"><a href="https://2007.igem.org/Berkeley_UC_Introduction">Introduction</a><br> | ||
</span><a TITLE="Hemoglobin production and maintenance is essential for oxygen delivery."><br> | </span><a TITLE="Hemoglobin production and maintenance is essential for oxygen delivery."><br> | ||
- | Oxygen Transport </a> </p> | + | <span class="style31">Oxygen Transport </span></a> </p> |
<ul> | <ul> | ||
<li class="style29"><span class="style29"><a TITLE="Human hemoglobin alpha is our choice of oxygen carrier." href="https://2007.igem.org/Berkeley_UC_OxygenTransport_Hemoglobin">Hemoglobin</a></span></li> | <li class="style29"><span class="style29"><a TITLE="Human hemoglobin alpha is our choice of oxygen carrier." href="https://2007.igem.org/Berkeley_UC_OxygenTransport_Hemoglobin">Hemoglobin</a></span></li> | ||
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</li> | </li> | ||
</ul> | </ul> | ||
- | <a TITLE="Our bacterial chassis has been heavily modified to remove its sepsis-inducing toxicity, immunogenic factors, and ability to grow within the bloodstream, as well as promote its ability to last longer in the bloodstream by masking it from the immune system. | + | <a href="https://2007.igem.org/Berkeley_UC_Immunity" TITLE="Our bacterial chassis has been heavily modified to remove its sepsis-inducing toxicity, immunogenic factors, and ability to grow within the bloodstream, as well as promote its ability to last longer in the bloodstream by masking it from the immune system." class="style31">Immunity</a> |
<ul class="style29"> | <ul class="style29"> | ||
<li><a TITLE="Our bacterial chassis has been modified to resist destruction by the immune system.">Chassis</a></li> | <li><a TITLE="Our bacterial chassis has been modified to resist destruction by the immune system.">Chassis</a></li> | ||
<li><a TITLE="A deletion of the msbB gene allows our chassis to be less immunogenic." href="https://2007.igem.org/Berkeley_UC_Immunity_msbBDeletion">msbB Deletion</a></li> | <li><a TITLE="A deletion of the msbB gene allows our chassis to be less immunogenic." href="https://2007.igem.org/Berkeley_UC_Immunity_msbBDeletion">msbB Deletion</a></li> | ||
</ul> | </ul> | ||
- | <p><a | + | <p><a href="https://2007.igem.org/Berkeley_UC_GrowthControl" TITLE="Growth is engineered to only occur in vitro." class="style31">Growth Control</a></p> |
<ul class="style29"><li><a TITLE="Antioxidants help to prevent damage by superoxide radicals." href="https://2007.igem.org/Berkeley_UC_Antioxidants" class="style29">Antioxidants</a> | <ul class="style29"><li><a TITLE="Antioxidants help to prevent damage by superoxide radicals." href="https://2007.igem.org/Berkeley_UC_Antioxidants" class="style29">Antioxidants</a> | ||
<ul> | <ul> | ||
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</a></li> | </a></li> | ||
</ul> | </ul> | ||
- | <p><span class="style28"><a href="https://2007.igem.org/Berkeley_UC_KillSwitch" TITLE="To prevent chance of infection or unwanted proliferation after hemoglobin production." class="style28">Genetic Self Destruct</a></span></p> | + | <p><span class="style28"><span class="style31"><a href="https://2007.igem.org/Berkeley_UC_KillSwitch" TITLE="To prevent chance of infection or unwanted proliferation after hemoglobin production." class="style28">Genetic Self Destruct</a></span></span></p> |
- | <p class=" | + | <p class="style31"><a TITLE="The Controller is an integrated genetic circuit comprised of two plasmids that allows stable maintenance of the system's various operons on a large single-copy plasmid in a dormant state. Upon induction, the copy number of the operons and their transcription increase 100-fold resulting in a dramatic increase in protein expression." href="https://2007.igem.org/Berkeley_UC_SystemController">SystemController</a></p> |
- | <span class=" | + | <span class="style31"><a TITLE="To enable preservation of our bacteria for long time periods, we are including the ability to produce the compounds hydroxyectoine and trehalose that will enable our bacteria to survive freeze-drying intact. This will dramatically increase shelf-life and decrease transport costs." href="https://2007.igem.org/Berkeley_UC_Storage" class="style28">Storage</a></span></div> |
<p class="style17"> </p> | <p class="style17"> </p> | ||
<p class="style17"> </p> | <p class="style17"> </p> |
Revision as of 11:13, 13 October 2007