Template:BerkiGEM2007 AustinOtherDetoxInformation

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Revision as of 07:28, 31 July 2007 by AustinDay (Talk | contribs)

AustinDay 02:21, 31 July 2007 (EDT)


This guy was using recombinant e coli to break down the very similar agricultural nerve agents. They used a mosquito esterase gene put into e. coli which expressed it on its surface. This leads me to the question of ... will sarin or other toxic nerve agents be able to pass through the cell membrane in order for the bacteria to break it down? How do I find out?

  • This other dude (I have all the refs on my computer, the wiki isn't very good for this) Has identified various phosphotriesterases that will detoxify a variety of organophosphates (pesticides, as well as the chemical weapons sarin and soman). He describes various mutants and their effects on the stereoselectivity.