ETHZ/Simulations
From 2007.igem.org
Contents |
Basic Model
Constitutively produced proteins
Learning system
Reporter system
System Equations
Model Parameters
| Parameter | Value | Description |
|---|---|---|
| aR | basic production of lacI | |
| aS | basic production of tetR | |
| aL | basic production of luxR | |
| aQ1 | basic production of cI | |
| aQ2 | basic production of p22cII | |
| aGFP | basic production of GFP | |
| aRFP | basic production of RFP | |
| dR | degradation of lacI | |
| dS | degradation of tetR | |
| dL | degradation of luxR | |
| dQ1 | degradation of cI | |
| dQ2 | degradation of p22cII | |
| dGFP | degradation of GFP | |
| dRFP | degradation of RFP | |
| kR | 0.22 [mM/h] | promoter strength (Promoter R0010) |
| kS | promoter strength (Promoter R0040) | |
| kL | promoter strength (Promoter R0062) | |
| kQ1 | 0.20 [mM/h] | promoter strength (Promoter R0051) |
| kQ2 | promoter strength (Promoter R0053) | |
| KR | 2e-3 [mM/h] | lacI repressor dissociation constant |
| KIR | 1.5e-10 [mM/h] | IPTG-lacI repressor dissociation constant |
| KS | tetR repressor dissociation constant | |
| KIS | aTc-tetR repressor dissociation constant | |
| KL | luxR activator dissociation constant | |
| KIL | AHL-luxR activator dissociation constant | |
| KQ1 | 2e-3 [mM/h] | cI repressor dissociation constant |
| KQ2 | p22cII repressor dissociation constant | |
| nR | 1 | lacI repressor Hill cooperativity |
| nIR | 2 | IPTG-lacI repressor Hill cooperativity |
| nS | tetR repressor Hill cooperativity | |
| nIS | aTc-tetR repressor Hill cooperativity | |
| nL | luxR activator Hill cooperativity | |
| nIL | AHL-luxR activator Hill cooperativity | |
| nQ1 | 1.9 | cI repressor Hill cooperativity |
| nQ2 | p22cII repressor Hill cooperativity |
Variable Mapping
| Variable | Compound |
|---|---|
| R | lacI |
| IR | IPTG |
| S | tetR |
| IS | aTc |
| L | luxR |
| IL | AHL |
| Q1 | cI |
| Q2 | p22cII |
