Template:BerkiGEM2007 AustinAlcoholInformation
From 2007.igem.org
AustinDay 01:42, 31 July 2007 (EDT)
- Can we create an injectable bacterium that can make you sober up quickly? I dunno, let's figure it out.
- I think we want Class I alcohol dehydrogenases.
- The first step catalyzed by the alcohol dehydrogenase is the limiting step right now.
- The second enzyme, acetaldehyde dehydrogenase will break down the very toxic acetaldehyde to acetic acid, which you pee out.
- This might be a good place to use John's scaffolding technology to fuse the two enzymes together to reduce the concentration of the toxic intermediate? That'd be fun.