Template:BerkiGEM2007 AustinAlcoholInformation

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Revision as of 05:42, 31 July 2007 by AustinDay (Talk | contribs)
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AustinDay 01:42, 31 July 2007 (EDT)

  • I think we want Class I alcohol dehydrogenases.
  • The first step catalyzed by the alcohol dehydrogenase is the limiting step right now.
  • The second enzyme, acetaldehyde dehydrogenase will break down the very toxic acetaldehyde to acetic acid, which you pee out.
  • This might be a good place to use John's scaffolding technology to fuse the two enzymes together to reduce the concentration of the toxic intermediate? That'd be fun.