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Edinburgh > DivisionPopper

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Division PoPer

Project Description

The aim is to create a signal generator device that produces an output of PoPS as a function of bacterial cell division. Down stream of the device there may be a counter device or a frequency analyser.

The system may for example perform pre-determined actions such as programmed cell death after a set number of cell divisions.

The device relies on using dif recombinase sites to flip once during each cell division. We hope to further analyse cell division and recombinase mechanisms since bacterial cell division is still relatively poorly understood.

We have constructed the bricks required for the first proof of concept experiment.