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From 2007.igem.org
It's clear that k1=0.1 and K1=0.5 doesn't ensure a correct behavior of the system: the repression of PHO8 is too weak when the oleic acid concentration becomes greater than 7.1 mM! We repeated the same analysis for the varying parameters K2 and K3 and we found that a good behavior is given by k2=1 and k3=0.1. This is confirmed be the following pictures: