Template:BerkiGEM2007 WikiPlaying

From 2007.igem.org

Revision as of 00:03, 9 October 2007 by Samanthaliang (Talk | contribs)












Untitled Document

Best viewed in the most recent version of firefox, because IE sucks.
The global demand and importance for cheap, available, and disease free blood substitutes is undisputed. There are currently no red blood cell substitutes approved for clinical use in the US or the UK, and whole blood is almost always in short supply. Underdeveloped countries that need blood the most simply don’t have the infrastructure to support donation and storage, in addition a sizeable fraction of the population are disease carriers. We are developing an innovative and cheap blood substitute based on engineered E. coli with all the critical properties of human erythrocytes. These include the ability to safely exist in the bloodstream, carry oxygen, and be stored for prolonged periods in a freeze-dried state.

Introduction

Oxygen Transport

Immunity

  • Chassis
  • msbB Deletion

Antioxidants

  • SodC/KatG

Growth Control

  • tonB Deletion
  • dapD Deletion

Kill Switch

SystemController

Storage