Tokyo/Formulation/4.population model

From 2007.igem.org

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次に,個体数をN個体にした式で表してみる.
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Next, to consider the number of cells,the differential equations for multiple cells were given as
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また,AHLは細胞膜をfreelyに透過と論文に記載あり.よって,細胞の中と外のAHLは同じとした.
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Next, introduce the equation with the number of the cells expressed as n.
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Here the concentration of AHL is assumed the same inside and outside of a cell according to the description that AHL is freely permiable through cell membrane in the referenced article.
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<br>[[Image:expression4-1.jpg|400px|]]
<br>[[Image:expression4-1.jpg|400px|]]
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<br>ここでもこれまでと同様相平面解析を行う.その際,N個体中の1個体に着目して相平面解析を行う.
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<br>where N indicates the number of the cells.
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<br>定常状態では,
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<br>Analyze the phaseplane with the focus on an individual among n cells.
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<br>In the steady state,time derivatives are zero.As a result,the nullclines of this system were derived as
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<br>In the steady state,  
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<br>[[Image:expression4-2.jpg|400px|]]
<br>[[Image:expression4-2.jpg|400px|]]
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<br>となり,3番目の式を2番目の式に代入する.
 
<br>and then substitute the third equation into the second
<br>and then substitute the third equation into the second
[[Image:parameter4-1.jpg|thumb|150px|]]
[[Image:parameter4-1.jpg|thumb|150px|]]
<br>[[Image:expression4-3.jpg|400px|]]
<br>[[Image:expression4-3.jpg|400px|]]
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<br>パラメータは右の表の値を用いた.相平面解析を行った結果,
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<br>To analyze the equations, the values in the right table were used.
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<br>The aprameter were determined by the values in the right table. The result of the phaseplane analysis,
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Revision as of 13:42, 23 October 2007

Next, to consider the number of cells,the differential equations for multiple cells were given as


Expression4-1.jpg


where N indicates the number of the cells.


In the steady state,time derivatives are zero.As a result,the nullclines of this system were derived as


Expression4-2.jpg


and then substitute the third equation into the second

Parameter4-1.jpg


Expression4-3.jpg


To analyze the equations, the values in the right table were used.