USTC/SuXiaofeng
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For obtaining the signaling transduction parts of repression with high fidelity, I've experimentally designed and acquired some specific repressor-promoter pairs(R-P pairs or P-R pairs)based on Lactose Operon by directed evolution on plate. Besides, through quantitative assay,the novel artificial R-P pairs I selected have been tested for their binding performance so that P-R pairs of highest affinity and specificity can make a figure out of P-R pair candidates. Most of the parts in my work have been BioBricks-Standardized and work as BioBrick parts. | For obtaining the signaling transduction parts of repression with high fidelity, I've experimentally designed and acquired some specific repressor-promoter pairs(R-P pairs or P-R pairs)based on Lactose Operon by directed evolution on plate. Besides, through quantitative assay,the novel artificial R-P pairs I selected have been tested for their binding performance so that P-R pairs of highest affinity and specificity can make a figure out of P-R pair candidates. Most of the parts in my work have been BioBricks-Standardized and work as BioBrick parts. | ||
- | [[Image:USTC_allen1.jpg|thumb]] | + | [[Image:USTC_allen1.jpg|thumb|center|500px|My project description by visual comics: All we need are the specific artificial 'repressor fish' that can definitely bite the specific 'operator hook' exclusively]] |
Revision as of 18:31, 19 October 2007
XIAOFENG SU
Undergruduate Student of Cellular and Molecular Biology,USTC
Email: allensue@mail.ustc.edu.cn (preference) or xiaofsu@gmail.com
Phone: +86-551-3602469 (Lab)
Mobile: +86-13866722084
Address: Room 439, School of Life Sciences, USTC, Hefei, Anhui, P.R.China, 230026
Research Interest
- Directed Evolution for Seeking New Protein-DNA Interactions
- Approaches of Synthetic Biology for Forming Novel "Genetic Engineering Machines"
- Differentiation and Development of Stem Cells
Research Work
- Overall Description
For obtaining the signaling transduction parts of repression with high fidelity, I've experimentally designed and acquired some specific repressor-promoter pairs(R-P pairs or P-R pairs)based on Lactose Operon by directed evolution on plate. Besides, through quantitative assay,the novel artificial R-P pairs I selected have been tested for their binding performance so that P-R pairs of highest affinity and specificity can make a figure out of P-R pair candidates. Most of the parts in my work have been BioBricks-Standardized and work as BioBrick parts.