Mathematical Models

From 2007.igem.org

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|On June 1st 2007, a group of undergraduate of various disciplines and from around the country assembled at NCBS, to attempt a 'proof of principle' demonstration. Their mission: to assemble and test a 'genetically engineered machine', a complex network assembled from simple biological parts. You will be amazed how much they managed to achieve in just six weeks!
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|On June 1st 2007, a group of undergraduates of various disciplines and from around the country assembled at NCBS, to attempt a 'proof of principle' demonstration. Their mission: to assemble and test a 'genetically engineered machine', a complex network assembled from simple biological parts. You will be amazed how much they managed to achieve in just six weeks!
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''The National Centre for Biological Sciences is a research institute located in Bangalore, India. In 2006, a team of graduate students from NCBS was the first from India to participate in iGEM. This year, we are very excited to compete as an all-undergraduate team of six students, from six different colleges located in four cities around India. Now that the summer is over, we hope hope to take the excitement of iGEM back to our home institutions, and create new teams across India who will participate in future iGEMs.''
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''The National Centre for Biological Sciences is a research institute located in Bangalore, India. In 2006, a team of graduate students from NCBS was the first from India to participate in iGEM. This year, we are very excited to compete as an all-undergraduate team of six students, from six different colleges located in four cities around India. Now that the summer is over, we hope to take the excitement of iGEM back to our home institutions, and create new teams across India who will participate in future iGEMs.''
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==Modeling our networks==
==Modeling our networks==
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*[[Media:Model.pdf|The system]]
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At the very beginning of our six weeks at NCBS, we spent our time designing experimental protocols, and learning how to mathematically model genetic networks. We decided to build models of our most complicated systems, the two stand-alone closed-loops: LuxR in feedback (I726091) and LuxI in feedback (I726101).
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*[[Media:Model.pdf|The systems]]
*[[Media:derivation_ai.pdf|Autoinducer diffusion]]
*[[Media:derivation_ai.pdf|Autoinducer diffusion]]
*[[Media:derivation_luxrstar.pdf|LuxR activation]]
*[[Media:derivation_luxrstar.pdf|LuxR activation]]

Latest revision as of 07:21, 24 October 2007

On June 1st 2007, a group of undergraduates of various disciplines and from around the country assembled at NCBS, to attempt a 'proof of principle' demonstration. Their mission: to assemble and test a 'genetically engineered machine', a complex network assembled from simple biological parts. You will be amazed how much they managed to achieve in just six weeks!
Ncbs Logo.jpg

The National Centre for Biological Sciences is a research institute located in Bangalore, India. In 2006, a team of graduate students from NCBS was the first from India to participate in iGEM. This year, we are very excited to compete as an all-undergraduate team of six students, from six different colleges located in four cities around India. Now that the summer is over, we hope to take the excitement of iGEM back to our home institutions, and create new teams across India who will participate in future iGEMs.

Ncbs.jpg
[http://www.ncbs.res.in/ National Centre for Biological Sciences, Bangalore]


Home The Team The Goal Parts Data Sheets Mathematical Models e-Notebook



Modeling our networks

At the very beginning of our six weeks at NCBS, we spent our time designing experimental protocols, and learning how to mathematically model genetic networks. We decided to build models of our most complicated systems, the two stand-alone closed-loops: LuxR in feedback (I726091) and LuxI in feedback (I726101).