Virginia Tech/Updates/Modeling

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<html><h3>Welcome to the 2007 Virginia Tech iGEM wiki!</h3></html>
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This wiki is under construction! While you’re waiting, check out our internally hosted wiki [https://wiki.vbi.vt.edu/display/SBGi/iGEM+2007 here].
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<html><center><A href="https://2007.igem.org/Virginia_Tech" target=_top><h3><FONT color=#ff8c00>Home</FONT></h3></A></center></html>
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[[Image: VtiGEM_crest_orange.JPG | 200px | Virginia Tech iGEM 2007]]
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<html><center><A href="https://2007.igem.org/Virginia_Tech/Project" target=_top><h3><FONT color=#ff8c00>Project</FONT></h3></A></center></html>
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<html><center><A href="https://2007.igem.org/Virginia_Tech/Team" target=_top><h3><FONT color=#ff8c00>Team</FONT></h3></A></center></html>
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<html><A href="https://2007.igem.org/Virginia_Tech/Project" target=_top><FONT color=#ff8c00>Project</FONT></A></html>
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<html><center><A href="https://2007.igem.org/Virginia_Tech/Photos" target=_top><h3><FONT color=#ff8c00>Photo Gallery</FONT></h3></A></center></html>
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<html><center><A href="https://2007.igem.org/Virginia_Tech/JC" target=_top><h3><FONT color=#ff8c00>Journal Club</FONT></h3></A></center></html>
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<html><center><A href="https://2007.igem.org/Virginia_Tech/Links" target=_top><h3><FONT color=#ff8c00>Links</FONT></h3></A></center></html>
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<html><center><A href="mailto:igem@vt.edu" target=_top><h3><FONT color=#ff8c00>Contact
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</FONT></h3></A></center></html>
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<html><A href="https://2007.igem.org/Virginia_Tech/Updates" target=_top><FONT color=#ff8c00>Progress Updates</FONT></A></html>
 
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<html><A href="https://2007.igem.org/Virginia_Tech/Photos" target=_top><FONT color=#ff8c00>Photo Gallery</FONT></A></html>
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<center><h1><font color="#ff8c00"> Modeling Updates:  
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<center><h3><font color="#8b0000"> VT iGEM Project 2007: Engineering an Epidemic</font></h3></center>
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<html><A href="https://2007.igem.org/Virginia_Tech/JC" target=_top><FONT color=#ff8c00>Journal Club</FONT></A></html>
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<p><h3>Introduction: Modeling the Epidemic</h3>
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Our Model of infection with and spread of an epidemic has two major levels:
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<li><b>A model for the infection of one population with the virus.</b> This model uses differential equations and chemical reactions to predict what happens over time given an initial number of phage and bacteria. For our lab experiments, this model will tell us what happens in each single well of the 96 in the microtiter plate.</li>
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<li><b>A model of the spread of the virus among populations as they interact.</b> This model will predict the spread of infection between populations of E. coli grown in a 96 well plate. We will use a Automated Liquid Handling Machine to mix the wells in a variety of patterns, for example, simple diffusion and in a network based on air traffic data.</li>
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We also originally started hoping to have a third and smallest layer: a gene network model. See below for an update.</p>
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<p><h3>Updates</h3></p>
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<html><A href="https://2007.igem.org/Virginia_Tech/Links" target=_top><FONT color=#ff8c00>Links</FONT></A></html>
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<p>'''Model Level 1: Gene Network Model'''</p>
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<p>We decided to put the work on the gene network model on hold because the model is very complex and difficult to accurately construct and its impact on the overall results is questionable.  Thus we are focusing our attention on other more vital aspects of the project for now and will hopefully return to working on this model towards the end of the summer if time permits. </p>
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<p>'''<html><a href="https://2007.igem.org/Virginia_Tech/Updates/Modeling/Infection_Model">Model Level 2: One Population Infection Model</a></html>'''</p>
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Contact
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<p>'''<html><a href="https://2007.igem.org/Virginia_Tech/Updates/Modeling/PopInter_Model">Model Level 3: Spread of an Epidemic between Populations</a></html>'''</p>
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<center><h3><font color="#8b0000"> Thanks to our Sponsors:</font></h3></center>
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<html><a href=" http://www.thirdsecurity.com "><img src="http://openwetware.org/images/3rdsecurity_logo.jpg "></a></html><br>
 
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[[Image: 3rdsecurity_logo.jpg| [3rd Security]]]
 
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[[Image: DNA20_logo.jpg| [http://www.dnatwopointo.com DNA 2.0]]]
 
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[[Image: VBI_logo.jpg| [http://www.vbi.vt.edu Virginia Bioinformatics Institute]]]
 
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[[Image: COE_logo.JPG| [http://www.eng.vt.edu/main/index.php VT College of Engineering]]]
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<html><center><A href="https://2007.igem.org/Virginia_Tech/Updates" target=_top><h3><FONT color=#ff8c00>Return to Progress Updates</FONT></h3></A></center></html>
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[[Image: COS_logo.jpg| [http://www.cos.vt.edu VT College of Science]]]
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[[Image: CALS_logo.JPG| [http://www.cals.vt.edu VT College of Agriculture and Life Sciences]]]
 
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Latest revision as of 16:15, 24 July 2007

Home

Home

Project

Team

Photo Gallery

Journal Club

Links

Contact


Modeling Updates:

VT iGEM Project 2007: Engineering an Epidemic

Introduction: Modeling the Epidemic

Our Model of infection with and spread of an epidemic has two major levels:

  • A model for the infection of one population with the virus. This model uses differential equations and chemical reactions to predict what happens over time given an initial number of phage and bacteria. For our lab experiments, this model will tell us what happens in each single well of the 96 in the microtiter plate.
  • A model of the spread of the virus among populations as they interact. This model will predict the spread of infection between populations of E. coli grown in a 96 well plate. We will use a Automated Liquid Handling Machine to mix the wells in a variety of patterns, for example, simple diffusion and in a network based on air traffic data.

We also originally started hoping to have a third and smallest layer: a gene network model. See below for an update.

Updates

Model Level 1: Gene Network Model

We decided to put the work on the gene network model on hold because the model is very complex and difficult to accurately construct and its impact on the overall results is questionable. Thus we are focusing our attention on other more vital aspects of the project for now and will hopefully return to working on this model towards the end of the summer if time permits.

Model Level 2: One Population Infection Model

Model Level 3: Spread of an Epidemic between Populations


Return to Progress Updates


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