Journal Club 08

14:30pm, Apr 15th Sun, [[Biotechnology building]]

==Future Plan Summary==
Due to the registration fee ($1000) due at May 30th, we need to find support quickly. The most convenient way is to convince Prof. Ouyang to give us support either by financing us with 20K RMB, or help us to get that money from the University. We have to work out all the proposals, in a greater detail, in one month. So we discussed and developed a rather detailed schedule for the next month. We will have the first selection procedure before May 1, separation of our team to work on the remaining projects individually during the May vacation, and a second selection procedure at the end of the vacation to choose the final 2 projects. The last 1 week is for the whole team to work out an official proposal and presentations, including the whole specification part and most of the design part of our projects.

Next meeting will be the last journal club in which new ideas can be proposed, although no literal material is required and more information can be added before May 1. Please hurry to work out the ideas if you have more.

==Tianjin Workshop==
{| 
| align="center" | 7:00 
| 北大东门集合
|-
| align="center" | 7:30 
| 五道口乘城铁 + 地铁
|-
| align="center" | 9:00 
| 北京站
|-
| align="center" | 9:20-10:40 
| 火车出发到天津站
|-
| align="center" | 10:40-1:00 
| 午饭，到达
|}

CFO: Liu Xili

Expected expense: RMB 100 / person

==Biobricks==
Presented by Lou Chunbo

===Riboswitch===
Aptamer + rbs; sensitive to small molecules; tandem use of the aptamer region; fast response.

===Self-killing system===
Material: Purine nucleoside phosphorylase (PNP) enzyme / 6-Methyparine PDR (6-MPDR)

PNP enzyme can hydrolyze 6-MPDR to produce 6-methypurine.

Use this method to kill cancer cells?

利用病毒侵染传入PNP（定向问题？）。再喂6-MPDR。细胞分裂即死。

===Tunable Quorum Sensing===

Add a LacI or CI binding site along with the original LuxR binding site at the Lux promoter. IPTG as a means to tune the quorum sensitivity of the population.

This is an interesting device, but we need further information about its application.

==Team Registration==
Team registration deadline: Apr 30. Website: [http://www.igem2007.com http://www.igem2007.com]

A two-page proposal due on May 1.

Registration fee = USD 1000 (due May 30)
+ USD 100 * Undergrads (due Nov)
+ USD 225 * Postgrads (due Nov).

Parts will be mailed to us in early May. We need to claim to the Custom.
* 院系级公章。
* 声明不可抽检。

==Schedule for our activities in the coming month==

===[[Journal Club 09]]===
Date: Apr 22
* 总结天津workshop。
* 提出ideas的最后期限，不要求文字proposal。

===[[Journal Club 10]]===
Date: Apr 28 or 29 afternoon (may extend to evening)
* ideas的材料补充。把能讲的都讲出来。
* 将ideas按相似性分为n组。（n=2 or 3）
* 队员分为n组。

===[[May vacation]]===
* 各组提出各自idea的项目目标和设计框架。五一之后提出文字proposal。

===[[Journal Club 11]]===
Date: May 6
* 筛选出2个projects。
* 队员重新分组。两个projects并行进行，在未来一周内做出正式proposal和presentation。

After we started: high frequency (twice a week) sub-group meeting