Edinburgh

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[[Image:800px-Edinburgh_City_15_mod.JPG|Banner]]
[[Image:800px-Edinburgh_City_15_mod.JPG|Banner]]
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=='''Welcome to Edinburgh's iGEM2007 Wiki'''==                                             
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Our wiki describes the two projects we have undertaken this summer, and the team responsible for their innovation.  Follow the links below to find out about the University of Edinburgh iGEM2007 team and the two projects we undertook.
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{|style="background:#cedff2    ; border:1px solid #afa3bf; padding: 1em; margin: auto"
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== The Team! ==
 
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{| width="20%" align="right"
 
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|[https://2007.igem.org/Edinburgh/Team https://static.igem.org/mediawiki/2007/0/0f/EdinburghTeam.jpg]
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This year the team is composed by 8 undergraduate/graduate students and three supervisors from three different schools within the University of Edinburgh (Biology, Engineering and Informatics).
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[[Edinburgh/Team|Click here]] to see our ugly faces and to know more about us.
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<h5 style="margin:0; background:#d0e5f5; font-size:140%; font-weight:bold; border:1px solid #abd5f5; text-align:center; padding:0.3em 0.4em; color: white;">'''[[Edinburgh/Team|The Team]]'''</h5>
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== The Project! ==
 
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Currently have two projects we are looking to take forward:
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[[Image:Team photo2.JPG|900 px]]
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=== Bacterial counter ===
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Our student team members in order: '''Luca Gerosa''' (Informatics), '''Sharon Wang''' (Biotechnology), '''Joe Rokicki''' (Engineering), '''Pradeep Ravindranath''' (Informatics & Biotechnology), '''Sarah Hollingshead''' (Biochemistry), '''Da Yin''' (Informatics) and '''Alistair Marshall''' (Engineering)
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[[Image:Cell division.jpg|right|Operons Overview|482x137px]]
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'''Project Goal'''
 
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The aim is to produce output as a function of cell division. This can have the added potential of performing programmed cell death after a determined number of divisions. We also hope to further analyse cell division and recombinase mechanisms.
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<center>(Game: Try to find '''Caroline Dahl''' (Biochemistry) in the picture.. :P)</center>
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=== Self flavouring yoghurt ===
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Link to [https://2007.igem.org/Edinburgh/Team team page]
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'''Project Goal'''
 
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Engineer lactic acid bacteria, such as ''Lactobacillus acidiphilus'' to synthesise flavours and colours during yoghurt production.  The idea is to stimulate the synthesis of a certain flavour and colour via the addition of an external stimulus.  Due to the nature of the finished product we will be using promoters induced by the disaccharides maltose, trehalose and arabinose.
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== The Projects! ==
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We are currently working on two projects:
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{|align="center" style="text-align:center; background:#fffaf5; border:1px solid #a3bfb1; padding: 1em; margin: auto" width="100%"
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The project will be carried out in two steps.  The first step is to generate the flavour and colour biosynthesis pathways in E. coli, before transferring them to ''Lactobacillus''.
 
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{| style="text-align: center;width:90%;"
 
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! |Targets||||Operons Overview
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| [[Edinburgh/DivisionPopper| '''<big>Division PoPper</big>''']]
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| [[Edinburgh/Yoghurt| '''<big>Self Flavouring Yoghurt</big>''']]
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* Insert a biobrick into a non E. coli bacterium (Bacillus Sublillis)
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* Engineer a pathway to make Vanillin
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|rowspan="3" width="80"|
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|rowspan="3"|[[Image:Yoghurt Operons.JPG| Operons Overview|421x316px]]
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|[https://2007.igem.org/Edinburgh/DivisionPopper https://static.igem.org/mediawiki/2007/6/64/Edinburgh_DivisionPic.jpg]
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|[https://2007.igem.org/Edinburgh/Yoghurt https://static.igem.org/mediawiki/2007/9/97/Edinburgh_Yogurt.jpg]
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|We designed a signal generator device that produces an output in the form of PoPS pulses each time a bacteria undergoes cell division. Therefore it may trigger actions as a function of cell replication.
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{|style="text-align: center; background:#8ae234; border:3px solid"
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|We aimed to develop flavour and colour biosynthesis pathways for potential use in 'self flavouring yoghurt' & a plasmid which would enable biobrick expression in gram positive bacteria
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! Potential Flavours|| Potential Colours
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| Vanilla|| Orange
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| Strawberry|| Red
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| Lemon || Yellow
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| Orange|| Pink
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== Links ==
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==IP Talk==
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Here are some links: 
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* [[Edinburgh/Ideas | Ideas]] - Projects that never came to be.
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* [[Edinburgh/Intellectual_Property_Talk| IP talk]] - A Synthetic Biology and Intellectual Property talk given to a local technology group.
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* [http://www.macteria.co.uk Macteria.co.uk] - Edinburgh's iGEM team website, with details of Edinburghs projects both past and present.
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Some members of the team presented a talk on Synthetic Biology and Intellectual Property to the Linux Users Group in Edinburgh
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==Our Sponsors ==
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More information can be found at [[Edinburgh/Intellectual Property Talk]]
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We would like to say a big thank you to our sponsors (below), who enabled us to compete in iGEM2007 this year
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== Links ==
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{|align="center" style="text-align:center;"
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[[Image:se_ia_rgb_x.jpg]][[Image:synbiocomm.jpg]]
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|-
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| [http://www.syntheticbiology.ethz.ch/synbiocomm/index https://static.igem.org/mediawiki/2007/8/8f/Synbiocomm.jpg]
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| [http://www.geneart.com/ https://static.igem.org/mediawiki/2007/5/50/Geneart_Logo.png]
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|-
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| colspan="2" align="center"|[http://www.scottish-enterprise.com/ https://static.igem.org/mediawiki/2007/1/1a/Se_ia_rgb_x.jpg][http://www.edinburghcampaign.ed.ac.uk/ https://static.igem.org/mediawiki/2007/d/d0/Campaign_logo.JPG]
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| [http://www.epsrc.ac.uk/default.htm https://static.igem.org/mediawiki/2007/0/04/EPSRC1RGBLO.jpg]
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| [http://www.bbsrc.ac.uk/ https://static.igem.org/mediawiki/2007/8/8f/Bbsrclogo.gif]
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==Disclaimer==
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[http://en.wikipedia.org/wiki/Help:Wikitext_examples "How to write in a Wiki" Manual] <br>
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Click on the [[Edinburgh/Disclaimer | Disclaimer]] link.
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[http://partsregistry.org/Main_Page Registry of Standard Biological Parts] <br>
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[http://openwetware.org/images/0/0d/Nature04342.pdf Foundations of Synthetic Biology Paper on Nature by Drew Endy] <br>
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[http://parts2.mit.edu/wiki/index.php/Resources Link to the teaching material in the last year iGEM wiki]<br>
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Latest revision as of 21:33, 4 March 2008

Banner


Contents

Welcome to Edinburgh's iGEM2007 Wiki

Our wiki describes the two projects we have undertaken this summer, and the team responsible for their innovation. Follow the links below to find out about the University of Edinburgh iGEM2007 team and the two projects we undertook.

The Team


Team photo2.JPG

Our student team members in order: Luca Gerosa (Informatics), Sharon Wang (Biotechnology), Joe Rokicki (Engineering), Pradeep Ravindranath (Informatics & Biotechnology), Sarah Hollingshead (Biochemistry), Da Yin (Informatics) and Alistair Marshall (Engineering)


(Game: Try to find Caroline Dahl (Biochemistry) in the picture.. :P)

Link to team page


The Projects!

We are currently working on two projects:

Division PoPper Self Flavouring Yoghurt
https://static.igem.org/mediawiki/2007/6/64/Edinburgh_DivisionPic.jpg https://static.igem.org/mediawiki/2007/9/97/Edinburgh_Yogurt.jpg
We designed a signal generator device that produces an output in the form of PoPS pulses each time a bacteria undergoes cell division. Therefore it may trigger actions as a function of cell replication. We aimed to develop flavour and colour biosynthesis pathways for potential use in 'self flavouring yoghurt' & a plasmid which would enable biobrick expression in gram positive bacteria

Links

Here are some links:

  • Ideas - Projects that never came to be.
  • IP talk - A Synthetic Biology and Intellectual Property talk given to a local technology group.
  • [http://www.macteria.co.uk Macteria.co.uk] - Edinburgh's iGEM team website, with details of Edinburghs projects both past and present.

Our Sponsors

We would like to say a big thank you to our sponsors (below), who enabled us to compete in iGEM2007 this year

[http://www.syntheticbiology.ethz.ch/synbiocomm/index https://static.igem.org/mediawiki/2007/8/8f/Synbiocomm.jpg] [http://www.geneart.com/ https://static.igem.org/mediawiki/2007/5/50/Geneart_Logo.png]
[http://www.scottish-enterprise.com/ https://static.igem.org/mediawiki/2007/1/1a/Se_ia_rgb_x.jpg][http://www.edinburghcampaign.ed.ac.uk/ https://static.igem.org/mediawiki/2007/d/d0/Campaign_logo.JPG]
[http://www.epsrc.ac.uk/default.htm https://static.igem.org/mediawiki/2007/0/04/EPSRC1RGBLO.jpg] [http://www.bbsrc.ac.uk/ https://static.igem.org/mediawiki/2007/8/8f/Bbsrclogo.gif]

Disclaimer

Click on the Disclaimer link.

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