USTC

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=== Our Project:<BR>Extensible Logic Circuit in Bacteria ===
=== Our Project:<BR>Extensible Logic Circuit in Bacteria ===
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Artificial Cell Signaling Network (ACS Network) and Integrated Circuit Network (IC Network) are both signaling networks. Now we are enjoying the advantage of Ultra Large Scale IC (ULSI), but at least today we cannot implement a somewhat large ACS Network in actual experiments.
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Logic Artificial Biologic Circuit (ABC) and logic Integrated Circuit(IC) are both composed by logic gates and wires. Now we are enjoying the advantage of Ultra Large Scale IC (ULSI), but at least today we cannot implement a somewhat large logic ABC containing several levels of logic gates in actual experiments.
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Our project is to provide a new viewpoint for building up fully extensible ACS Networks. We are going to produce biologic logic gates such as NAND, NOR, NOT for some biological conveniences. In other words, modern logic IC Networks are built upon these three gates-- NAND, NOR and NOT. Logic gates are only the basic elements of logic IC, on the other hand, the more important factors we think which make IC Network to be easily enlarged are: Reducing the scale of elements; Tuning elements to eliminate interference; Calibrating elements for interconnection. Cis-acting elements may provide smaller scale than trans-acting ones, while the other two factors can be achieved by standardization. We will present the method for standardization and demonstrate an ACS Network made by these biologic logic gates.
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Our project is to provide a new methodology for building up fully extensible logic ABC. We are going to produce biologic logic gates such as NAND, NOR, NOT for some biological conveniences. In other words, modern logic IC are built upon these three gates-- NAND, NOR and NOT. Logic gates are only the basic components of logic IC, on the other hand, the more important factors we think which make IC to be easily enlarged are: reducing the size, power and response time of components; tuning components to eliminate interference; calibrating components for interconnection. Cis-acting elements may provide smaller scale than trans-acting ones, while the other two factors can be achieved by novelly designed wires and standardization. We will also demonstrate an ABC made by these biologic logic gates.
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This ACS Network may not be large, but the important factors we implement in it will naturally make it fully extensible. IC has been born for 50 years and how hugely it impacts our modern life! So, what about biologic logic circuit in next 50 years? A new world is waiting...
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This ABC may not be large, but the important factors we implement in it will naturally make it fully extensible. IC has been born for 50 years and how hugely it impacts our modern life! So, what about biologic logic circuit in next 50 years? A new world is waiting...

Revision as of 08:51, 2 August 2007


USTC Logo.png

Our Project:
Extensible Logic Circuit in Bacteria

Logic Artificial Biologic Circuit (ABC) and logic Integrated Circuit(IC) are both composed by logic gates and wires. Now we are enjoying the advantage of Ultra Large Scale IC (ULSI), but at least today we cannot implement a somewhat large logic ABC containing several levels of logic gates in actual experiments.

Our project is to provide a new methodology for building up fully extensible logic ABC. We are going to produce biologic logic gates such as NAND, NOR, NOT for some biological conveniences. In other words, modern logic IC are built upon these three gates-- NAND, NOR and NOT. Logic gates are only the basic components of logic IC, on the other hand, the more important factors we think which make IC to be easily enlarged are: reducing the size, power and response time of components; tuning components to eliminate interference; calibrating components for interconnection. Cis-acting elements may provide smaller scale than trans-acting ones, while the other two factors can be achieved by novelly designed wires and standardization. We will also demonstrate an ABC made by these biologic logic gates.

This ABC may not be large, but the important factors we implement in it will naturally make it fully extensible. IC has been born for 50 years and how hugely it impacts our modern life! So, what about biologic logic circuit in next 50 years? A new world is waiting...


DSCN1243.png

From left to right
Back row: Zhao Yun, Liu Ziqing, Ma Xiaoyu
Front row: Ma Rui, Su Xiaofeng, Ding Bo, Zhan Jian

Events

01/08/2007
Ma Rui: There is a mistake in my preparing X-Gal solution. Please rework your correlative experiments. Sorry!

30/07/2007
First designed repressors. Good work, Bo and Xiaofeng!

22/06/2007
Sruggling for the final-examinations.

01/06/2007
Primary experiments begin around this day.

Previous

Tasks


PoPS Convertors

Biologic Logic Gates

Promoter Designing

Lac Repressor Redesigning

Fluorescent Reporters

All Things Together Linking

Wiki Construction

Presentation and Poster


Members

Graduates:
Zhan Jian
Ding Bo
Ma Rui
Ma Xiaoyu

Undergraduates:
Su Xiaofeng
Liu Ziqing
Zhao Yun

Faculty Advisors:
Prof. HY Liu
Prof. JR Wu
Prof. ZH Hou

Resources

Modeling Utilities

Protocols

Promoter Design

Service Providers

Gallery

Team Photos

Laboratory

[http://sg.ustc.edu.cn/mediawiki/index.php/IGEM_USTC_2007:USTCPhotos USTC Photos]

[http://sg.ustc.edu.cn/mediawiki/index.php/IGEM_USTC_2007:HuangshanPhotos Huangshan Mountain]

Links

[http://partsregistry.org iGEM standard parts' catalog ]

[http://www.ustc.edu.cn Univ. of Sci. and Tech. of China ]

[http://groups.google.com/group/iGEMChina iGEM China Group]


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