1. Concept & Model

The goal of our project is to make a bacterial society that follows Pareto's principle as an ant society does. On the other word, we try to construct a bacterial system which takes "balanced differentiation".(See more.)

1. Differentiation　⇒　2. Worker Removal
　3. Dedifferentiation ⇒　4.Redifferentiation

2. Requirements

Bistability and cell-cell communication are necessary to realize our model of "Balanced differentiation". (See more.)


1．Differentiation generated by mutual-inhibition circuit.
2．cell-cell communication .

3. Genetic circuit

The genetic circuit in this project consisted of the new parts as well as BioBrick parts. (See more.)

The new parts of this year are here!!

4. Works

Our model has been sophisticated though successive combinations of wet and dry approaches. (See more.)

Wet assay

Dry simulation
Using the data from wet experiments

5. About our team

Students
Satoru Akama | Kenichiro Iwasaki | Hiroki Kawahara | Hajime Nakatani

Advisors: Last year's member
Shotaro Ayukawa | Akio Kobayashi

Instructors
[http://www.sb.dis.titech.ac.jp/ Daisuke Kiga] | [http://www.es.dis.titech.ac.jp/ Masayuki Yamamura] | [http://nicosia.is.s.u-tokyo.ac.jp/~hagiya/ Masami Hagiya] | [http://www.sb.dis.titech.ac.jp/ Masahiko Uchiyama]

Reference