Paris/Elementary rules
From 2007.igem.org
(Difference between revisions)
Revision as of 10:16, 3 August 2007
In Bacteria:
DAP + Export -> DAP_Export // Diffusion (from a pump) DAP_Import -> DAP + Import //
Cre -> . // Degradation (inside) DAP -> . //
DAPAp + DAP <-> DAPAp_i // Promotor Activity DAPAp -> DAPAp + Cre // DAPAp_i -> DAPAp_i + Cre (low probability) //
LOXP_Box + 4Cre -> DAP_Box + 4Cre // Differentiation DAP_Box -> DAP_Box + DAP // DAP Production
Out Bacteria:
x:Bact \/ LOXP_Box -> x1 + x2 // Division* (under control of Ftsz A or not ?)
DAP + (x \/ Import) -> DAP_Import :: x // Diffusion x \/ DAP_Export -> DAP + (Export :: x) //
DAP -> . // DAP Degradation (outside)
- Doubling of the genetic material + random repartition of the others molecules between the two "daughters"
notes:
\ /: means "with" LOXP_Box: is inside the germinal line
DAP_Box: is the LOXP_Box recombined, is inside the somatic line
- there is a low probability, that DAP is able to act alone.
- we don't know yet, if CRE need 4 molecules or if it is a cooperative fixation
- in the division, we have take care of the DAP affinity for the promotor.
- dependence of the germinal line for DAP:
- if hight concentration (does she died ?) - if low concentration ( slow down of the division)--> death's dependence for the level of the DAP