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E.coli Follow Pareto's principle!

To follow Pareto’s principle like an ant society, our model system must follow the three conditions shown in Fig. 1 to 3. In our model, all nodes (individual cells) have the same genetic circuits but take two states, A (worker) and B (idler), depending on the surrounding circumstances.

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Condition 1. Bistable state

Fig. 1 The system is stable when it contains both A (worker) and B (idler) at certain ratio.

Condition 2. Unstable state with node A removedまだ「node」が残っている！

Fig. 2 By removal of A (worker), the system containing only B (idler)becomes unstable.

Condition 3. From unstable to stable state

Fig. 3 In the unstable state, some B (idler) changes to A (worker) while the others remain B (idler). Then the system becomes stable again.