Edinburgh/Yoghurt

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Introduction | Applications | Objectives | Design | Modelling | Wet Lab | References


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Welcome to the self flavouring yogurt project!


The aim of this project is not only to produce colourful, tasty yoghurt, but to demostrate it is possible to successfully introduce biobricks into gram positive organisms.


We chose to produce 'self flavouring' yoghurt, as this project enables us to genetically manipulate a range of gram positive bacteria required for yoghurt formation (see yoghurt production, below).

Bacillus subtilis, Smith AC & Hussey M

There are several advantages for using genetically engineered gram positive bacteria, over the traditionally used E. coli, a few of these include:

  • Gram positive organisms are food grade, and therefore may be ingested. Potentially this could enable their use in a range of products from medicines to milk shakes or yoghurt to deliver benifical molecules to the body
  • Several gram positive bacteria, such as Bacillus spp are able to form hardy spores. These do not require refridgeration and can be transported and used in very hot, cold or developing countries cheaply and with ease
  • Gram positive organisms, such as the lactic acid bacteria, are much more efficient at secreting proteins and other molecules into their surrounding media than E. coli.


Yoghurt Production


Introduction | Applications | Objectives | Design | Modelling | Wet Lab | References