Tokyo/alternative

From 2007.igem.org

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<!--リプレッサーA,B,シグナル分子Sの時間変化を式として表し、安定性解析を行った結果、Hill係数が大切であることがわかった
<!--リプレッサーA,B,シグナル分子Sの時間変化を式として表し、安定性解析を行った結果、Hill係数が大切であることがわかった

Revision as of 16:08, 22 October 2007

Title2.JPG

1. Abstruct

Concept & Model

A bacterial society designed in this project follows Pareto's principle as an Ant society does. To realize this model, the behaviors of the model - bistability of each individual and the system's stability under the coexsistence of the two types - have been confirmed in silico and in virto.
Tokyo simulation s2.jpg
Our goal.JPG

This model is based on two principles - bistability and coexistence by cell-cell communication. See more.


2. Works

2-a. Genetic circuits

2-b. Combinatione of Wet & Dry

Wet 1: Hybrid promoter

The newly deviced hybrid promoter regulated by two inputs.- the presence of AHL and the absence of LacI, that is, the presence of IPTG.

Hybridgraph.JPG

Dry 1: Formulation

なんとかなんとか。See more.

2. Wet : Assay set 1

For the parameters of Hill coefficients by AHL and IPTG assays
See more.
Hill AHL.JPG|Hill IPTG.JPG

3. Dry : Simulation set 2

なんとかなんとか。See more.

4. Wet : Assay set 2

For the other parameters. See more.

5. Future works

Continue this combinational approaches to sophisticate our model. See more.


3. About our team

Students
Satoru Akama | Kenichiro Iwasaki | Hiroki Kawahara | Hajime Nakatani

Advisors: Last year's member
Shotaro Ayukawa | Akio Kobayashi

Instructors
[http://www.sb.dis.titech.ac.jp/ Daisuke Kiga] | [http://www.es.dis.titech.ac.jp/ Masayuki Yamamura] | [http://nicosia.is.s.u-tokyo.ac.jp/~hagiya/ Masami Hagiya] | [http://www.sb.dis.titech.ac.jp/ Masahiko Uchiyama]

Links sunaba