Tokyo/sunaba
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| - | <br> In the worker ants, we can find true workers and idlers even though they have the same genome. In the abscence of the ture workers, a part of idlers become the true worker. | + | <br> In the worker ants, we can find true workers and idlers even though they have the same genome. In the abscence of the ture workers, a part of idlers become the true worker. We tried to construct such society of bacteria. |
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| + | ===[[Tokyo/Requirements |Requirements]]:<br> bistability and cell-cell communication=== | ||
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Revision as of 10:01, 21 October 2007
砂場。
1,Project summaryConcept& model: Bacterial society that follows Pareto's principle like ant society
Requirements:
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2,WorksApproach:We alternated approach of Wet and Dry.2-0.Wet : Hybrid promoter
2-1.Dry : FormulationWe wrote the Formulation 2-2.Wet : AssayWe decided the parameter of hill coefficients by the assay of AHL & IPTG
2-3.Dry : Simulationwet実験で求められたパラメータを用いて、集団が怠け者の細胞のみとなった場合に、一度不安定化して、続いて働き者と怠け者になれることをStocastic Simulationで確認した。このシステムの挙動に必要な他のパラメータ範囲が判明した。
2-4.Wet : AssaySimulationを満たすための他のパラメータが現在のプラスミドで可能であるかを、大腸菌を用いた実験で確認した。
2-5.Future works3,About our team
Advisors: Last year's member
Instructors
Links sunaba
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