Tokyo/Formulation/5.stochastic differential equation model with poisson random variables

From 2007.igem.org

< Tokyo/Formulation(Difference between revisions)
 
(34 intermediate revisions not shown)
Line 1: Line 1:
 +
__NOTOC__
 +
<br>[[Tokyo/Works|Works top]]  0.[[Tokyo/Works/Hybrid promoter|Hybrid promoter]]  1.[[Tokyo/Works/Formulation |Formulation]]  2.[[Tokyo/Works/Assay |Assay1]]  '''3.[[Tokyo/Works/Simulation |Simulation]]'''  4.[[Tokyo/Works/Assay2 |Assay2]]  5.[[Tokyo/Works/Future works |Future works]]
 +
<br><br>[[Tokyo/Formulation/1.toggle model |Step1]]  [[Tokyo/Formulation/2.toggle model with hybrid promoter |Step2]]  [[Tokyo/Formulation/3.AHL-experssing model|Step3]]  [[Tokyo/Formulation/4.population model|Step4]]  [[Tokyo/Formulation/5.stochastic differential equation model with poisson random variables|Step5]]
 +
<br>
 +
== ==
we introduced the terms of [[Tokyo/Formulation/4.population model|Ex 4-1]] into a stochastic process to simulate the sthochastic behavior.we used Poisson random variables as a sthochastic process. Threfore,a stochastic differential equations were given as
we introduced the terms of [[Tokyo/Formulation/4.population model|Ex 4-1]] into a stochastic process to simulate the sthochastic behavior.we used Poisson random variables as a sthochastic process. Threfore,a stochastic differential equations were given as
-
<br>[[Image:expression5-1.jpg|500px|left|thumb|Ex 5-1]][[Image:parameter4-1.jpg|150px|none|thumb|Table 5]]
+
<br>[[Image:expression5-1.jpg|500px|none|thumb|Ex 5-1]]
 +
<!--[[Image:parameter4-1.jpg|150px|none|thumb|Table 5]]-->
 +
 
 +
 
 +
 
 +
''' ここより下は独立したページにすべき? '''
 +
<!--
<br>The values of parameters in the right table were used and the results of simulation were shown in Fig 5.1-3.
<br>The values of parameters in the right table were used and the results of simulation were shown in Fig 5.1-3.
 +
 +
<br>where α2 = 1(μM) in Fig 5.1,α2 = 2.7(μM) in Fig 5.2,α2 = 4(μM) in Fig 5.3. and it has been estimated that 1(μM) = 1000 molecules (count).
<br>where α2 = 1(μM) in Fig 5.1,α2 = 2.7(μM) in Fig 5.2,α2 = 4(μM) in Fig 5.3. and it has been estimated that 1(μM) = 1000 molecules (count).
-
[[Image:3d-1-0.2.JPG|270px|left|thumb|Figure 5.1.A   t=0.2(min)]]
+
<br>Fig.5.1 indicates that all cells shift to A state in the steady state and Fig 5.3 indicates that all cells shift to B state in the steady state.These results doesn't represent coexistence stable.
-
[[Image:3d-1-0.8.JPG|270px|left|thumb|Figure 5.1.B   t=0.8(min)]]
+
<br>Fig.5.2 indicates that a portion of cells shift to A state and the others shift to B state in steady state;that is,individual cells are stable under stable coexistence.
-
[[Image:3d-1-30.JPG|270px|none|thumb|Figure 5.1.C   t=30(min)    failure only A]]
+
 
 +
[[Image:3d-1-0.2.JPG|200px|left|thumb|Figure 5.1.A   t=0.2(min)]]
 +
[[Image:arrow2.JPG|50px|left|thumb]]
 +
[[Image:3d-1-0.8.JPG|200px|left|thumb|Figure 5.1.B   t=0.8(min)]]
 +
[[Image:arrow2.JPG|50px|left|thumb]]
 +
[[Image:3d-1-30.JPG|200px|none|thumb|Figure 5.1.C   t=30(min) only A]]
 +
===[[Tokyo/Formulation/5.stochastic differential equation model with poisson random variables/only A movie/|movie here!!]]===
 +
 
<br>
<br>
-
[[Image:3d-2.7-0.2.JPG|270px|left|thumb|Figure 5.2.A   t=0.2(min)]]
+
[[Image:3d-2.7-0.2.JPG|200px|left|thumb|Figure 5.2.A   t=0.2(min)]]
-
[[Image:3d-2.7-0.8.JPG|270px|left|thumb|Figure 5.2.B   t=0.8(min)]]
+
[[Image:arrow2.JPG|50px|left|thumb]]
-
[[Image:3d-2.7-30.JPG|270px|none|thumb|Figure 5.2.C   t=30(min)  success!!          coexistence]]
+
[[Image:3d-2.7-0.8.JPG|200px|left|thumb|Figure 5.2.B   t=0.8(min)]]
 +
[[Image:arrow2.JPG|50px|left|thumb]]
 +
[[Image:3d-2.7-30.JPG|200px|none|thumb|Figure 5.2.C   t=30(min)'''  success!!          coexistence''']]
 +
 
 +
===[[Tokyo/Formulation/5.stochastic differential equation model with poisson random variables/ A and B coexistence movie/ |movie here!!]]===
 +
 
<br>
<br>
-
[[Image:3d-4-0.2.JPG|270px|left|thumb|Figure 5.3.A   t=0.2(min)]]
+
[[Image:3d-4-0.2.JPG|200px|left|thumb|Figure 5.3.A   t=0.2(min)]]
-
[[Image:3d-4-0.8.JPG|270px|left|thumb|Figure 5.3.B   t=0.8(min)]]
+
[[Image:arrow2.JPG|50px|left|thumb]]
-
[[Image:3d-4-30.JPG|270px|none|thumb|Figure 5.3.C   t=30(min)   failure only B]]
+
[[Image:3d-4-0.8.JPG|200px|left|thumb|Figure 5.3.B   t=0.8(min)]]
 +
[[Image:arrow2.JPG|50px|left|thumb]]
 +
[[Image:3d-4-30.JPG|200px|none|thumb|Figure 5.3.C   t=30(min)  '''  only B''']]
 +
 
 +
===[[Tokyo/Formulation/5.stochastic differential equation model with poisson random variables/only B movie/|movie here!!]]===
 +
 
 +
 
 +
 
 +
 
 +
<br>Next,the relation between the results of simulation and phase plane are shown in Fig.5.4.1-3,where the nullclines of this system were [[Tokyo/Formulation/4.population model|Ex 4-3]]
 +
 
 +
[[Image:phase plane and simulation-1.JPG|270px|left|thumb|Figure 5.4.1]]
 +
[[Image:phase plane and simulation-2.7.JPG|270px|left|thumb|Figure 5.4.2]]
 +
[[Image:phase plane and simulation-4.JPG|270px|none|thumb|Figure 5.4.3]]
 +
 
 +
<br>Fig.5.4.1-3 indicate that the distribution of the cells corresponds with the stable equilibrium points.
 +
-->
-
<br>パラメータを3種類使ってシミュレーションした結果が以下である.
+
== ==
-
これとstep4のdetermineの相平面とを比べるとこうですよ.
+
[[Tokyo/Formulation/5.stochastic differential equation model with poisson random variables|Step.5]] >> [[Tokyo/Works/Formulation|Formulation TOP]]

Latest revision as of 13:03, 25 October 2007


Works top  0.Hybrid promoter  1.Formulation  2.Assay1  3.Simulation  4.Assay2  5.Future works

Step1  Step2  Step3  Step4  Step5

we introduced the terms of Ex 4-1 into a stochastic process to simulate the sthochastic behavior.we used Poisson random variables as a sthochastic process. Threfore,a stochastic differential equations were given as


Ex 5-1


ここより下は独立したページにすべき?

Step.5 >> Formulation TOP