Latest revision as of 03:34, 27 October 2007

Welcome!

The IC GEMs team consists of ten 2nd year undergraduates from Bioengineering and Bioscience. Our genuine collective interest in healthcare led to the targetting of health and medicine related applications this year. Together with the vision of an industry, the strategy we adopted for our projects is to use the Engineering Cycle to create reliable Synthetic Biology products where standards and quality control are strictly kept.

Main Project - Infector Detector

Infector Detector is a system that will detect the presence of biofilm infections on urinary catheters by reporting on the presence of AHL, a signalling molecule used by E.coli, and output a fluorescent protein as a result. (more...)

Main Achievements

Designed and modelled a device to detect biofilms and prevent urinary catheter infections like MRSA
Successfully utilized cell-free chassis for Infector Detector
Characterised Infector Detector to detect AHL at ambient temperatures
Compared system expression to AHL Receiver (BBa_F2620) transfer function.

Foundational technology - Cell-Free Systems

Power your iGEM projects with Cell-Free Systems! Find out what this new chassis has done for us, and what it can do for you! (more...)

Sub Project - Cell by Date

Cell by Date will report when ground beef has been out of the cold chain for too long. It produces fluorescent proteins at ambient temperatures above 8°C. (more...)

Main Achievements

Designed and modelled a device to indicate spoilage of meat/break in the cold chain via the thermal history of the system
Utilised project results to characterise cell-free chassis
Characterised pTet-GFP and pT7-GFP under isothermal conditions

Meet the Team

Open Science on OpenWetWare

We did Open Science!

Our projects were run and organised using OWW, with updates on a day-to-day basis! Click here to access our 400+ pages of full documentation!

Contributions to Registry

Chassis Additions

Cell-Free Systems
- Homemade E. coli S30
- Commercial E. coli S30
- Commercial E. coli T7 S30
- Vesicle Encapsulation

Part/Construct Additions

T7 promoter (BBa_I719005)
pT7 with GFP reporter (BBa_I719015)

Part/Construct Characterisation

AHL Receiver (BBa_F2620)
pTet GFP (BBa_I13522)
pLux GFP (BBa_J37032)

Fun with iGEM

Pictures, Quotes and More!

Acknowledgements

IC Deputy Rector's Fund
IC Faculty of Engineering
IC Faculty of Natural Sciences
European Commission, Synbiocomm Project

@@ Line 1: / Line 1: @@
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 <html>
-<link rel="stylesheet" href="/igem07/index.php?title=User:Alexander.wong/Stylesheets/mainpage.css&action=raw&ctype=text/css" type="text/css" />
+<link rel="stylesheet" href="/igem07/index.php?title=User:Dirkvs/Stylesheets/mainpage.css&action=raw&ctype=text/css" type="text/css" />
 <div id="wrap">
 	<div id="maincontent">
@@ Line 12: / Line 11: @@
 	<div id="OverviewBox">
-				<h2>Our Approach</h2>
+				<h2><b>Welcome!</b></h2>
-		<div class="contentbox">Our genuine interest in healthcare led to the targetting of <b>health and medicine related applications</b> this year. Together with the vision of an industry, the strategy we adopted for our projects is to use the Engineering Cycle to create reliable Synthetic Biology products where standards and quality control are strictly kept.
+		<div class="contentbox">The IC GEMs team consists of ten 2nd year undergraduates from Bioengineering and Bioscience. Our genuine collective interest in healthcare led to the targetting of <b>health and medicine related applications</b> this year. Together with the vision of an industry, the strategy we adopted for our projects is to use the Engineering Cycle to create reliable Synthetic Biology products where standards and quality control are strictly kept.
                  </div>
@@ Line 20: / Line 19: @@
 	<div id="FeatureBox">
 		<div class="contentbox">
-			<h2><b>Main Project</b> - <a href="https://2007.igem.org/Imperial/Infector_Detector/Introduction">Infector Detector</a></h2>
+			<h1><b>Main Project</b> - <a href="https://2007.igem.org/Imperial/Infector_Detector/Introduction">Infector Detector</a></h1>
-<br>
-<center><img src="https://static.igem.org/mediawiki/2007/3/32/IC07_cartoon.png" width="580px"></center>
+Infector Detector is a system that will detect the presence of biofilm infections on urinary catheters by reporting on the presence of AHL, a signalling molecule used by E.<i>coli</i>, and output a fluorescent protein as a result. (<a href="https://2007.igem.org/Imperial/Infector_Detector/Introduction">more...</a>)
-<table style="background-color: #f5facf;" width="580px" align="center" border="0" cellpadding="7px" cellspacing="5">
+<br><br>
+<table style="background-color: #f5facf;" width="590px" align="center" border="0" cellpadding="7px" cellspacing="5">
     <tr>
-       <td valign="top" style="text-align:justify;">Infector Detector is a system that will detect the presence of biofilm infections on urinary catheters by reporting on the presence of AHL, a signalling molecule used by E.<i>coli</i>, and output a fluorescent protein as a result. (<a href="https://2007.igem.org/Imperial/Infector_Detector/Introduction">more...</a>)<br>
+       <td valign="top" style="text-align:justify;">
+           <center><img src="https://static.igem.org/mediawiki/2007/d/d5/IC07_IDnews.png" width="260px"></center>
        </td>
        <td>
@@ Line 32: / Line 34: @@
 		<div class="parabox">
                         <ul>
-                        <li>Designed and modelled a device to detect biofilms and potentially prevent diseases like MRSA
+                        <li>Designed and modelled a device to <b>detect biofilms</b> and <b>prevent urinary catheter infections</b> like MRSA
-                        <li>Characterised Infector Detector in terms of various AHL concentrations, at room temperature
+                       <li>Successfully utilized <b>cell-free chassis</b> for Infector Detector
+                        <li>Characterised Infector Detector to <b>detect AHL at ambient temperatures</b>
+                       <li><a href="https://2007.igem.org/Imperial/Infector_Detector/F2620_Comparison"><b>Compared system expression</b></a> to <a href="http://partsregistry.org/Part:BBa_F2620">AHL Receiver (BBa_F2620)</a> transfer function.
                         </ul>
                  </div>
@@ Line 47: / Line 51: @@
 	<div id="TechnoBox">
 		<div class="contentbox">
-			<h2>Foundational technology - <a href="https://2007.igem.org/Imperial/Cell-Free/Whatis">Cell-Free Systems</a></h2>
+			<h2><b>Foundational technology</b> - <a href="https://2007.igem.org/Imperial/Cell-Free/Whatis">Cell-Free Systems</a></h2>
+<br>
 <center><img src="https://static.igem.org/mediawiki/2007/b/bb/IC07_CFS_components.png" width="400px"></center>
 <table style="background-color: #dff7d6;" width="560px" align="center" border="0" cellpadding="7px" cellspacing="5">
@@ Line 59: / Line 64: @@
 	<div id="FeatureBox">
 		<div class="contentbox">
-			<h2><b>Sub Project</b> - <a href="https://2007.igem.org/Imperial/Cell_by_Date/Introduction">Cell by Date</a></h2>
+			<h1><b>Sub Project</b> - <a href="https://2007.igem.org/Imperial/Cell_by_Date/Introduction">Cell by Date</a></h1>
+Cell by Date will report when ground beef has been out of the cold chain for too long. It produces fluorescent proteins at ambient temperatures above 8&deg;C. (<a href="https://2007.igem.org/Imperial/Cell_by_Date/Introduction">more...</a>)<br>
 <table style="background-color: #f5facf;" width="560px" align="center" border="0" cellpadding="7px" cellspacing="5">
     <tr>
-       <td valign="center"><img src="https://static.igem.org/mediawiki/2007/thumb/9/96/IC07_cellbydate.png/340px-IC07_cellbydate.png" width="200px">
+       <td valign="center"><img src="https://static.igem.org/mediawiki/2007/7/74/CBDCartoonfront.png" width="220px">
-       <td valign="top" style="text-align:justify;">Cell by Date will report when ground beef has been out of the cold chain for too long. It produces fluorescent proteins at ambient temperatures above 8&deg;C. (<a href="https://2007.igem.org/Imperial/Cell_by_Date/Introduction">more...</a>)<br>
+       <td valign="top" style="text-align:left;">
+           <div id="SummaryBox" style="width: 300px;">
-           <div id="SummaryBox">
 				<h2>Main Achievements</h2>
-		<div class="parabox">
+		<div class="parabox" style="width: 270px;">
                         <ul>
-                        <li>Designed and modelled a device to indicate spoilage of meat/break in the cold chain via the thermal history of the system
+                        <li>Designed and modelled a device to <b>indicate spoilage of meat</b>/break in the cold chain via the <b>thermal history</b> of the system
+                       <li> Utilised project results to <b>characterise cell-free chassis</b>
+                       <li> Characterised <a href="http://partsregistry.org/Part:BBa_I13522">pTet-GFP</a> and <a href="http://partsregistry.org/Part:BBa_I719015">pT7-GFP</a> under <b>isothermal conditions</b>
                         </ul>
                  </div>
@@ Line 112: / Line 120: @@
 		<h2><b><a href="https://2007.igem.org/Imperial/Team" title="">Meet the Team</a></b></h2>
 <br />
-<img src="https://static.igem.org/mediawiki/2007/2/24/IC07_teamphoto2.jpg" width="230px">
+<img src="https://static.igem.org/mediawiki/2007/9/97/IC07_teamphoto3.jpg" width="230px">
+<br>
 	</div>
-	<div class="post-it yellowbox">
+	<div class="post-it bluebox">
-		<h2><b><a href="https://2007.igem.org/Imperial/Fun" title="">Fun with iGEM</a></b></h2>
+		<h2><b> <a href="https://2007.igem.org/Imperial/Open_Science_on_OpenWetWare" title="">Open Science on OpenWetWare</a></b></h2>
-<br>
+   <table style="background-color: #d9f0f8; filter:alpha(opacity=80); -moz-opacity:0.8; font-size: .95em;">
-Channel 4 at Imperial College !
+         <tr style="font-weight: bold;">
-<object width="220" height="250"><param name="movie" value="http://www.youtube.com/v/A-mCWIGVgmQ&rel=1"></param><param name="wmode" value="transparent"></param><embed src="http://www.youtube.com/v/A-mCWIGVgmQ&rel=1" type="application/x-shockwave-flash" wmode="transparent" width="220" height="250"></embed></object>
+               <td>We did Open Science!</td>
+         </tr><tr>
+               <td>
+               Our projects were run and organised using OWW, with updates on a day-to-day basis! Click <a href="https://2007.igem.org/Imperial/Open_Science_on_OpenWetWare" title="">here to access our <b>400+ pages of full documentation!</b></a>
+               </td></tr>
+   </table>
 	</div>
 	<div class="post-it pinkbox">
 		<h2><b>Contributions to Registry</b></h2>
     <table style="background-color: #f0dbcc; filter:alpha(opacity=80); -moz-opacity:0.8; font-size: .95em;">
           <tr style="font-weight: bold;">
-                <td>Chassis</td>
+                <td>Chassis Additions</td>
           </tr><tr>
                 <td>
@@ Line 136: / Line 150: @@
                 </td></tr>
           <tr style="font-weight: bold;">
-                <td>Part Constructs</td>
+                <td>Part/Construct Additions</td>
           </tr><tr>
                 <td>
@@ Line 142: / Line 156: @@
                 <a href="http://partsregistry.org/Part:BBa_I719015">pT7 with GFP reporter (BBa_I719015)</a>
                 </td></tr>
-   </table>
-	</div>
-	<div class="post-it bluebox">
-		<h2><b><a href="https://2007.igem.org/Imperial/Open_Science_on_OpenWetWare" title="">Full Documentation on OWW</a></b></h2>
-   <table style="background-color: #d9f0f8; filter:alpha(opacity=80); -moz-opacity:0.8; font-size: .95em;">
           <tr style="font-weight: bold;">
-                <td>We did Open Science!</td>
+                <td>Part/Construct Characterisation</td>
           </tr><tr>
                 <td>
-                Entire project was run and organised using OWW, with updates on a day-to-day basis!
+                <a href="http://partsregistry.org/Part:BBa_F2620"> AHL Receiver (BBa_F2620)</a> <br>
-                </td></tr>
+               <a href="http://partsregistry.org/Part:BBa_I13522">pTet GFP (BBa_I13522)</a><br>
+               <a href="http://partsregistry.org/Part:BBa_J37032">pLux GFP (BBa_J37032)</a><br>
+                </td>
+         </tr>
     </table>
+	</div>
+	<div class="post-it yellowbox">
+		<h2><b><a href="https://2007.igem.org/Imperial/Fun" title="">Fun with iGEM</a></b></h2>
+   <table style="background-color: #f7fbd7; filter:alpha(opacity=80); -moz-opacity:0.8; font-size: .95em;">
+      <td> Pictures, Quotes and More!
+   </table>
 	</div>
@@ Line 164: / Line 184: @@
                 IC Faculty of Engineering<br>
                 IC Faculty of Natural Sciences<br>
-                European Commission, Synbiocomm Project<br><br>
+                European Commission, Synbiocomm Project<br>
-               <a href="http://www.geneart.com"><img src="http://www.geneart.com/fileadmin/templates/img/logo.gif" width="180"></a>
                 </td>
     </table>

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From 2007.igem.org

Latest revision as of 03:34, 27 October 2007

Welcome!

Main Project - Infector Detector

Main Achievements

Foundational technology - Cell-Free Systems

Sub Project - Cell by Date

Main Achievements

Meet the Team

Open Science on OpenWetWare

Contributions to Registry

Fun with iGEM

Acknowledgements