Imperial
From 2007.igem.org
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| - | <h2> | + | <h2><b>Welcome!</b></h2> |
| - | <div class="contentbox">Our | + | <div class="contentbox">The IC GEMs team consists of ten 2nd year undergraduates from Bioengineering and Bioscience. Our genuine collective interest in healthcare led to the targetting of <b>health and medicine related applications</b> this year. Together with the vision of an industry, the strategy we adopted for our projects is to use the Engineering Cycle to create reliable Synthetic Biology products where standards and quality control are strictly kept. |
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<div id="FeatureBox"> | <div id="FeatureBox"> | ||
<div class="contentbox"> | <div class="contentbox"> | ||
| - | < | + | <h1><b>Main Project</b> - <a href="https://2007.igem.org/Imperial/Infector_Detector/Introduction">Infector Detector</a></h1> |
| - | <table style="background-color: #f5facf;" width=" | + | Infector Detector is a system that will detect the presence of biofilm infections on urinary catheters by reporting on the presence of AHL, a signalling molecule used by E.<i>coli</i>, and output a fluorescent protein as a result. (<a href="https://2007.igem.org/Imperial/Infector_Detector/Introduction">more...</a>) |
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| + | <table style="background-color: #f5facf;" width="590px" align="center" border="0" cellpadding="7px" cellspacing="5"> | ||
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| - | + | <td valign="top" style="text-align:justify;"> | |
| - | + | <center><img src="https://static.igem.org/mediawiki/2007/d/d5/IC07_IDnews.png" width="260px"></center> | |
| - | <td valign="top" style="text-align:justify;"> | + | </td> |
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<div id="SummaryBox"> | <div id="SummaryBox"> | ||
<h2>Main Achievements</h2> | <h2>Main Achievements</h2> | ||
<div class="parabox"> | <div class="parabox"> | ||
<ul> | <ul> | ||
| - | <li>Designed and modelled a device to detect biofilms and | + | <li>Designed and modelled a device to <b>detect biofilms</b> and <b>prevent urinary catheter infections</b> like MRSA |
| - | <li>Characterised Infector Detector | + | <li>Successfully utilized <b>cell-free chassis</b> for Infector Detector |
| + | <li>Characterised Infector Detector to <b>detect AHL at ambient temperatures</b> | ||
| + | <li><a href="https://2007.igem.org/Imperial/Infector_Detector/F2620_Comparison"><b>Compared system expression</b></a> to <a href="http://partsregistry.org/Part:BBa_F2620">AHL Receiver (BBa_F2620)</a> transfer function. | ||
</ul> | </ul> | ||
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<div id="TechnoBox"> | <div id="TechnoBox"> | ||
<div class="contentbox"> | <div class="contentbox"> | ||
| - | <h2>Foundational technology - <a href="https://2007.igem.org/Imperial/Cell-Free/Whatis">Cell-Free Systems</a></h2> | + | <h2><b>Foundational technology</b> - <a href="https://2007.igem.org/Imperial/Cell-Free/Whatis">Cell-Free Systems</a></h2> |
| + | <br> | ||
| + | <center><img src="https://static.igem.org/mediawiki/2007/b/bb/IC07_CFS_components.png" width="400px"></center> | ||
| + | <table style="background-color: #dff7d6;" width="560px" align="center" border="0" cellpadding="7px" cellspacing="5"> | ||
| + | <td valign="top" style="text-align:justify;">Power your iGEM projects with Cell-Free Systems! Find out what this new chassis has done for us, and what it can do for you! (<a href="https://2007.igem.org/Imperial/Cell-Free/Whatis">more...</a>)<br> | ||
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<div id="FeatureBox"> | <div id="FeatureBox"> | ||
<div class="contentbox"> | <div class="contentbox"> | ||
| - | < | + | <h1><b>Sub Project</b> - <a href="https://2007.igem.org/Imperial/Cell_by_Date/Introduction">Cell by Date</a></h1> |
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| + | Cell by Date will report when ground beef has been out of the cold chain for too long. It produces fluorescent proteins at ambient temperatures above 8°C. (<a href="https://2007.igem.org/Imperial/Cell_by_Date/Introduction">more...</a>)<br> | ||
<table style="background-color: #f5facf;" width="560px" align="center" border="0" cellpadding="7px" cellspacing="5"> | <table style="background-color: #f5facf;" width="560px" align="center" border="0" cellpadding="7px" cellspacing="5"> | ||
<tr> | <tr> | ||
| - | <td valign="center"><img src="https://static.igem.org/mediawiki/2007/ | + | <td valign="center"><img src="https://static.igem.org/mediawiki/2007/7/74/CBDCartoonfront.png" width="220px"> |
| - | <td valign="top" style="text-align: | + | <td valign="top" style="text-align:left;"> |
| - | + | <div id="SummaryBox" style="width: 300px;"> | |
| - | <div id="SummaryBox"> | + | |
<h2>Main Achievements</h2> | <h2>Main Achievements</h2> | ||
| - | <div class="parabox"> | + | <div class="parabox" style="width: 270px;"> |
<ul> | <ul> | ||
| - | <li>Designed and modelled a device to indicate spoilage of meat/break in the cold chain via the thermal history of the system | + | <li>Designed and modelled a device to <b>indicate spoilage of meat</b>/break in the cold chain via the <b>thermal history</b> of the system |
| + | <li> Utilised project results to <b>characterise cell-free chassis</b> | ||
| + | <li> Characterised <a href="http://partsregistry.org/Part:BBa_I13522">pTet-GFP</a> and <a href="http://partsregistry.org/Part:BBa_I719015">pT7-GFP</a> under <b>isothermal conditions</b> | ||
</ul> | </ul> | ||
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<div class="post-it greenbox"> | <div class="post-it greenbox"> | ||
<h2><b><a href="https://2007.igem.org/Imperial/Team" title="">Meet the Team</a></b></h2> | <h2><b><a href="https://2007.igem.org/Imperial/Team" title="">Meet the Team</a></b></h2> | ||
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</div> | </div> | ||
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| - | <div class="post-it | + | <div class="post-it bluebox"> |
| - | <h2><b><a href="https://2007.igem.org/Imperial/ | + | <h2><b> <a href="https://2007.igem.org/Imperial/Open_Science_on_OpenWetWare" title="">Open Science on OpenWetWare</a></b></h2> |
| + | <table style="background-color: #d9f0f8; filter:alpha(opacity=80); -moz-opacity:0.8; font-size: .95em;"> | ||
| + | <tr style="font-weight: bold;"> | ||
| + | <td>We did Open Science!</td> | ||
| + | </tr><tr> | ||
| + | <td> | ||
| + | Our projects were run and organised using OWW, with updates on a day-to-day basis! Click <a href="https://2007.igem.org/Imperial/Open_Science_on_OpenWetWare" title="">here to access our <b>400+ pages of full documentation!</b></a> | ||
| + | </td></tr> | ||
| + | </table> | ||
</div> | </div> | ||
<div class="post-it pinkbox"> | <div class="post-it pinkbox"> | ||
| - | <h2><b | + | <h2><b>Contributions to Registry</b></h2> |
<table style="background-color: #f0dbcc; filter:alpha(opacity=80); -moz-opacity:0.8; font-size: .95em;"> | <table style="background-color: #f0dbcc; filter:alpha(opacity=80); -moz-opacity:0.8; font-size: .95em;"> | ||
<tr style="font-weight: bold;"> | <tr style="font-weight: bold;"> | ||
| - | <td>Chassis</td> | + | <td>Chassis Additions</td> |
</tr><tr> | </tr><tr> | ||
<td> | <td> | ||
| - | + | <a href="http://partsregistry.org/Chassis/Cell-Free_Systems">Cell-Free Systems</a><br> | |
| + | <a href="http://partsregistry.org/Chassis/Cell-Free_Systems/Homemade_E.coli_S30">- Homemade <i>E. coli</i> S30</a><br> | ||
| + | <a href="http://partsregistry.org/Chassis/Cell-Free_Systems/Commercial_E.coli_S30">- Commercial <i>E. coli</i> S30</a><br> | ||
| + | <a href="http://partsregistry.org/Chassis/Cell-Free_Systems/Commercial_E.coli_T7_S30">- Commercial <i>E. coli</i> T7 S30</a><br> | ||
| + | <a href="http://partsregistry.org/Chassis/Cell-Free_Systems/Vesicle">- Vesicle Encapsulation</a><br> | ||
</td></tr> | </td></tr> | ||
<tr style="font-weight: bold;"> | <tr style="font-weight: bold;"> | ||
| - | <td>Part | + | <td>Part/Construct Additions</td> |
</tr><tr> | </tr><tr> | ||
<td> | <td> | ||
| - | + | <a href="http://partsregistry.org/Part:BBa_I719005">T7 promoter (BBa_I719005)</a><br> | |
| + | <a href="http://partsregistry.org/Part:BBa_I719015">pT7 with GFP reporter (BBa_I719015)</a> | ||
</td></tr> | </td></tr> | ||
| + | <tr style="font-weight: bold;"> | ||
| + | <td>Part/Construct Characterisation</td> | ||
| + | </tr><tr> | ||
| + | <td> | ||
| + | <a href="http://partsregistry.org/Part:BBa_F2620"> AHL Receiver (BBa_F2620)</a> <br> | ||
| + | <a href="http://partsregistry.org/Part:BBa_I13522">pTet GFP (BBa_I13522)</a><br> | ||
| + | <a href="http://partsregistry.org/Part:BBa_J37032">pLux GFP (BBa_J37032)</a><br> | ||
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| + | </td> | ||
| + | </tr> | ||
</table> | </table> | ||
</div> | </div> | ||
| - | <div class="post-it | + | <div class="post-it yellowbox"> |
| - | <h2><b><a href=" | + | <h2><b><a href="https://2007.igem.org/Imperial/Fun" title="">Fun with iGEM</a></b></h2> |
| + | <table style="background-color: #f7fbd7; filter:alpha(opacity=80); -moz-opacity:0.8; font-size: .95em;"> | ||
| + | <td> Pictures, Quotes and More! | ||
| + | </table> | ||
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</div> | </div> | ||
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IC Faculty of Engineering<br> | IC Faculty of Engineering<br> | ||
IC Faculty of Natural Sciences<br> | IC Faculty of Natural Sciences<br> | ||
| - | European Commission, Synbiocomm Project<br | + | European Commission, Synbiocomm Project<br> |
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</td> | </td> | ||
</table> | </table> | ||
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Latest revision as of 03:34, 27 October 2007
Welcome!
The IC GEMs team consists of ten 2nd year undergraduates from Bioengineering and Bioscience. Our genuine collective interest in healthcare led to the targetting of health and medicine related applications this year. Together with the vision of an industry, the strategy we adopted for our projects is to use the Engineering Cycle to create reliable Synthetic Biology products where standards and quality control are strictly kept.
Main Project - Infector Detector
Infector Detector is a system that will detect the presence of biofilm infections on urinary catheters by reporting on the presence of AHL, a signalling molecule used by E.coli, and output a fluorescent protein as a result. (more...)
 |
Main Achievements
|
Foundational technology - Cell-Free Systems
| Power your iGEM projects with Cell-Free Systems! Find out what this new chassis has done for us, and what it can do for you! (more...) |
Sub Project - Cell by Date
Cell by Date will report when ground beef has been out of the cold chain for too long. It produces fluorescent proteins at ambient temperatures above 8°C. (more...)
|
Open Science on OpenWetWare
| We did Open Science! |
| Our projects were run and organised using OWW, with updates on a day-to-day basis! Click here to access our 400+ pages of full documentation! |
Contributions to Registry
| Chassis Additions |
|
Cell-Free Systems - Homemade E. coli S30 - Commercial E. coli S30 - Commercial E. coli T7 S30 - Vesicle Encapsulation |
| Part/Construct Additions |
|
T7 promoter (BBa_I719005) pT7 with GFP reporter (BBa_I719015) |
| Part/Construct Characterisation |
|
AHL Receiver (BBa_F2620) pTet GFP (BBa_I13522) pLux GFP (BBa_J37032) |
Fun with iGEM
| Pictures, Quotes and More! |
Acknowledgements
|
IC Deputy Rector's Fund IC Faculty of Engineering IC Faculty of Natural Sciences European Commission, Synbiocomm Project |
- This page was last modified on 27 October 2007, at 03:34.
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