Imperial

From 2007.igem.org

(Difference between revisions)
 
(45 intermediate revisions not shown)
Line 1: Line 1:
{{Template:IC07navmenu}}
{{Template:IC07navmenu}}
-
 
<html>
<html>
-
<link rel="stylesheet" href="/igem07/index.php?title=User:Alexander.wong/Stylesheets/mainpage.css&action=raw&ctype=text/css" type="text/css" />
+
<link rel="stylesheet" href="/igem07/index.php?title=User:Dirkvs/Stylesheets/mainpage.css&action=raw&ctype=text/css" type="text/css" />
<div id="wrap">
<div id="wrap">
<div id="maincontent">
<div id="maincontent">
Line 9: Line 8:
<div id="maincol">
<div id="maincol">
 +
<div id="OverviewBox">
<div id="OverviewBox">
-
<h2>Our Approach</h2>
+
<h2><b>Welcome!</b></h2>
-
<div class="contentbox">With the vision of an industry, the strategy for our projects this year is to use the Engineering Cycle to create reliable Synthetic Biology products where standards and quality control are strictly kept.
+
<div class="contentbox">The IC GEMs team consists of ten 2nd year undergraduates from Bioengineering and Bioscience. Our genuine collective interest in healthcare led to the targetting of <b>health and medicine related applications</b> this year. Together with the vision of an industry, the strategy we adopted for our projects is to use the Engineering Cycle to create reliable Synthetic Biology products where standards and quality control are strictly kept.
                 </div>
                 </div>
Line 19: Line 19:
<div id="FeatureBox">
<div id="FeatureBox">
<div class="contentbox">
<div class="contentbox">
-
<h2><b>Main Project</b> - <a href="https://2007.igem.org/Imperial/Infector_Detector/Introduction">Infector Detector</a></h2>  
+
<h1><b>Main Project</b> - <a href="https://2007.igem.org/Imperial/Infector_Detector/Introduction">Infector Detector</a></h1>  
-
<table style="background-color: #f5facf;" width="560px" align="center" border="0" cellpadding="7px" cellspacing="5">
+
Infector Detector is a system that will detect the presence of biofilm infections on urinary catheters by reporting on the presence of AHL, a signalling molecule used by E.<i>coli</i>, and output a fluorescent protein as a result. (<a href="https://2007.igem.org/Imperial/Infector_Detector/Introduction">more...</a>)
 +
<br><br>
 +
 
 +
<table style="background-color: #f5facf;" width="590px" align="center" border="0" cellpadding="7px" cellspacing="5">
   <tr>
   <tr>
-
      <td><img src="https://static.igem.org/mediawiki/2007/thumb/e/e6/IC07_biofilm.png/300px-IC07_biofilm.png" width="200px">
+
       <td valign="top" style="text-align:justify;">
-
 
+
          <center><img src="https://static.igem.org/mediawiki/2007/d/d5/IC07_IDnews.png" width="260px"></center>
-
       <td valign="top" style="text-align:justify;">Infector Detector is a system that will detect the presence of biofilm infections on urinary catheters by reporting on the presence of AHL, a signalling molecule used by E.<i>coli</i>, and output a fluorescent protein as a result. (<a href="https://2007.igem.org/Imperial/Infector_Detector/Introduction">more...</a>)<br>
+
      </td>
-
 
+
      <td>
           <div id="SummaryBox">
           <div id="SummaryBox">
<h2>Main Achievements</h2>
<h2>Main Achievements</h2>
<div class="parabox">
<div class="parabox">
                       <ul>
                       <ul>
-
                       <li>Designed and modelled a device to detect biofilms and potentially prevent diseases like MRSA
+
                       <li>Designed and modelled a device to <b>detect biofilms</b> and <b>prevent urinary catheter infections</b> like MRSA
-
                       <li>Characterised Infector Detector in terms of various AHL concentrations, at room temperature
+
                      <li>Successfully utilized <b>cell-free chassis</b> for Infector Detector
 +
                       <li>Characterised Infector Detector to <b>detect AHL at ambient temperatures</b>
 +
                      <li><a href="https://2007.igem.org/Imperial/Infector_Detector/F2620_Comparison"><b>Compared system expression</b></a> to <a href="http://partsregistry.org/Part:BBa_F2620">AHL Receiver (BBa_F2620)</a> transfer function.
                       </ul>
                       </ul>
                 </div>
                 </div>
Line 43: Line 48:
</div>   
</div>   
-
 
-
<!-- Place Team Photo under here -->
 
-
<img src="http://openwetware.org/images/1/1a/IC07_teamphoto.jpg" width="610px" >
 
<div id="TechnoBox">
<div id="TechnoBox">
<div class="contentbox">
<div class="contentbox">
-
<h2>Foundational technology - <a href="https://2007.igem.org/Imperial/Cell-Free/Whatis">Cell-Free Systems</a></h2>
+
<h2><b>Foundational technology</b> - <a href="https://2007.igem.org/Imperial/Cell-Free/Whatis">Cell-Free Systems</a></h2>
 +
<br>
 +
<center><img src="https://static.igem.org/mediawiki/2007/b/bb/IC07_CFS_components.png" width="400px"></center>
 +
<table style="background-color: #dff7d6;" width="560px" align="center" border="0" cellpadding="7px" cellspacing="5">
 +
      <td valign="top" style="text-align:justify;">Power your iGEM projects with Cell-Free Systems! Find out what this new chassis has done for us, and what it can do for you! (<a href="https://2007.igem.org/Imperial/Cell-Free/Whatis">more...</a>)<br>
-
<table style="background-color: #dff7d6;" width="560px" align="center" border="0" cellpadding="7px" cellspacing="5">
 
-
  <tr>
 
-
      <td valign="top" style="text-align:justify;">Power your iGEM projects with Cell-Free Systems! Select from the range of options available to suit your specification needs. Click <a href="https://2007.igem.org/Imperial/Cell-Free/Whatis">here</a> for more details!<br>
 
-
      </td>
 
-
      <td valign="top">
 
-
          <div id="SummaryBox">
 
-
<h2>Main Achievements</h2>
 
-
<div class="parabox">
 
-
                      <ul>
 
-
                      <li>Investigated and characterised the <i>in vitro</i> chassis
 
-
                      <li>Characterised the F2620, pTet-GFP and pT7-GFP construct <i>in vitro</i>
 
-
                      </ul>
 
-
                </div>
 
-
        </div>
 
-
      </td>
 
-
  </tr>
 
</table>
</table>
                 </div>
                 </div>
Line 74: Line 64:
<div id="FeatureBox">
<div id="FeatureBox">
<div class="contentbox">
<div class="contentbox">
-
<h2>Sub Project - <a href="https://2007.igem.org/Imperial/Cell_by_Date/Introduction">Cell by Date</a></h2>  
+
<h1><b>Sub Project</b> - <a href="https://2007.igem.org/Imperial/Cell_by_Date/Introduction">Cell by Date</a></h1>
 +
 
 +
Cell by Date will report when ground beef has been out of the cold chain for too long. It produces fluorescent proteins at ambient temperatures above 8&deg;C. (<a href="https://2007.igem.org/Imperial/Cell_by_Date/Introduction">more...</a>)<br>
<table style="background-color: #f5facf;" width="560px" align="center" border="0" cellpadding="7px" cellspacing="5">
<table style="background-color: #f5facf;" width="560px" align="center" border="0" cellpadding="7px" cellspacing="5">
   <tr>
   <tr>
-
       <td valign="center"><img src="https://static.igem.org/mediawiki/2007/thumb/9/96/IC07_cellbydate.png/340px-IC07_cellbydate.png" width="200px">
+
       <td valign="center"><img src="https://static.igem.org/mediawiki/2007/7/74/CBDCartoonfront.png" width="220px">
-
       <td valign="top" style="text-align:justify;">Cell by Date will report when ground beef has been out of the cold chain for too long. It produces fluorescent proteins at ambient temperatures above 8&deg;C. (<a href="https://2007.igem.org/Imperial/Cell_by_Date/Introduction">more...</a>)<br>
+
       <td valign="top" style="text-align:left;">
-
 
+
           <div id="SummaryBox" style="width: 300px;">
-
           <div id="SummaryBox">
+
<h2>Main Achievements</h2>
<h2>Main Achievements</h2>
-
<div class="parabox">
+
<div class="parabox" style="width: 270px;">
                       <ul>
                       <ul>
-
                       <li>Designed and modelled a device to indicate spoilage of meat/break in the cold chain via the thermal history of the system
+
                       <li>Designed and modelled a device to <b>indicate spoilage of meat</b>/break in the cold chain via the <b>thermal history</b> of the system
 +
                      <li> Utilised project results to <b>characterise cell-free chassis</b>
 +
                      <li> Characterised <a href="http://partsregistry.org/Part:BBa_I13522">pTet-GFP</a> and <a href="http://partsregistry.org/Part:BBa_I719015">pT7-GFP</a> under <b>isothermal conditions</b>
                       </ul>
                       </ul>
                 </div>
                 </div>
Line 126: Line 119:
<div class="post-it greenbox">
<div class="post-it greenbox">
<h2><b><a href="https://2007.igem.org/Imperial/Team" title="">Meet the Team</a></b></h2>
<h2><b><a href="https://2007.igem.org/Imperial/Team" title="">Meet the Team</a></b></h2>
 +
<br />
 +
<img src="https://static.igem.org/mediawiki/2007/9/97/IC07_teamphoto3.jpg" width="230px">
 +
<br>
 +
</div>
-
                    <table style="background-color: #dff7d6; filter:alpha(opacity=80); -moz-opacity:0.8; font-size: .95em;">
+
<div class="post-it bluebox">
-
                      <tr style="font-weight: bold;">
+
<h2><b> <a href="https://2007.igem.org/Imperial/Open_Science_on_OpenWetWare" title="">Open Science on OpenWetWare</a></b></h2>
-
                          <td>Undergraduates</td>
+
  <table style="background-color: #d9f0f8; filter:alpha(opacity=80); -moz-opacity:0.8; font-size: .95em;">
-
                          <td style="text-align: right; padding-left: 5px;">Faculty Advisors</td>
+
        <tr style="font-weight: bold;">
-
                      </tr>
+
              <td>We did Open Science!</td>
-
                      <tr>
+
        </tr><tr>
-
                          <td>James Chappell</td>
+
              <td>
-
                          <td style="text-align: right; padding-left: 5px;">Prof. Paul Freemont</td>
+
              Our projects were run and organised using OWW, with updates on a day-to-day basis! Click <a href="https://2007.igem.org/Imperial/Open_Science_on_OpenWetWare" title="">here to access our <b>400+ pages of full documentation!</b></a>
-
                      </tr>
+
              </td></tr>
-
                      <tr>
+
  </table>
-
                          <td>Lucas Hadjilucas</td>
+
-
                          <td style="text-align: right; padding-left: 5px;">Prof. Richard Kitney</td>
+
-
                      </tr>
+
-
                      <tr>
+
-
                          <td>Jaroslaw Karcz</td>
+
-
                          <td style="text-align: right; padding-left: 5px;"></td>
+
-
                      </tr>
+
-
                      <tr>
+
-
                          <td>Anthony Lazzaro</td>
+
-
                          <td style="text-align: right; font-weight:bold; padding-left: 5px;">Supervisors</td>
+
-
                      </tr>
+
-
                      <tr>
+
-
                          <td>Peixuan Pey</td>
+
-
                          <td style="text-align: right; padding-left: 5px;">Vincent Rouilly</td>
+
-
                      </tr>
+
-
                      <tr>
+
-
                          <td>Maira Tariq</td>
+
-
                          <td style="text-align: right; padding-left: 5px;">Matthieu Bultelle</td>
+
-
                      </tr>
+
-
                      <tr>
+
-
                          <td>Ben Yi Tew</td>
+
-
                          <td style="text-align: right; padding-left: 5px;">Kirsten Jensen</td>
+
-
                      </tr>
+
-
                      <tr>
+
-
                          <td>Cheuk Ka Tong</td>
+
-
                          <td style="text-align: right; padding-left: 5px;">Dr. Duo Lu</td>
+
-
                      </tr>
+
-
                      <tr>
+
-
                          <td>Dirk van Swaay</td>
+
-
                          <td style="text-align: right; padding-left: 5px;"></td>
+
-
                      </tr>
+
-
                      <tr>
+
-
                          <td>Alexander Wong</td>
+
-
                          <td></td>
+
-
                      </tr>
+
-
                    </table>
+
-
 
+
-
 
+
-
</div>
+
-
+
-
<div class="post-it yellowbox">
+
-
<h2><b><a href="https://2007.igem.org/Imperial/Fun" title="">Fun with iGEM</a></b></h2>
+
</div>
</div>
Line 185: Line 140:
   <table style="background-color: #f0dbcc; filter:alpha(opacity=80); -moz-opacity:0.8; font-size: .95em;">
   <table style="background-color: #f0dbcc; filter:alpha(opacity=80); -moz-opacity:0.8; font-size: .95em;">
         <tr style="font-weight: bold;">
         <tr style="font-weight: bold;">
-
               <td>Chassis</td>
+
               <td>Chassis Additions</td>
         </tr><tr>
         </tr><tr>
               <td>
               <td>
Line 195: Line 150:
               </td></tr>
               </td></tr>
         <tr style="font-weight: bold;">
         <tr style="font-weight: bold;">
-
               <td>Part Constructs</td>
+
               <td>Part/Construct Additions</td>
         </tr><tr>
         </tr><tr>
               <td>
               <td>
-
               Links to the relevant pages created
+
               <a href="http://partsregistry.org/Part:BBa_I719005">T7 promoter (BBa_I719005)</a><br>
 +
              <a href="http://partsregistry.org/Part:BBa_I719015">pT7 with GFP reporter (BBa_I719015)</a>
               </td></tr>
               </td></tr>
 +
        <tr style="font-weight: bold;">
 +
              <td>Part/Construct Characterisation</td>
 +
        </tr><tr>
 +
              <td>
 +
              <a href="http://partsregistry.org/Part:BBa_F2620"> AHL Receiver (BBa_F2620)</a> <br>
 +
              <a href="http://partsregistry.org/Part:BBa_I13522">pTet GFP (BBa_I13522)</a><br>
 +
              <a href="http://partsregistry.org/Part:BBa_J37032">pLux GFP (BBa_J37032)</a><br>
 +
 +
              </td>
 +
        </tr>
   </table>
   </table>
</div>
</div>
-
<div class="post-it greenbox">
+
<div class="post-it yellowbox">
-
<h2><b><a href="https://2007.igem.org/Imperial/Cell-Free/Whatis" title="">Cell-Free Systems</a></b></h2>
+
<h2><b><a href="https://2007.igem.org/Imperial/Fun" title="">Fun with iGEM</a></b></h2>
-
   <table style="background-color: #dff7d6; filter:alpha(opacity=80); -moz-opacity:0.8; font-size: .95em;">
+
   <table style="background-color: #f7fbd7; filter:alpha(opacity=80); -moz-opacity:0.8; font-size: .95em;">
-
  <tr style="font-weight: bold;">
+
      <td> Pictures, Quotes and More!
-
              <td>Foundational Technology</td>
+
-
        </tr><tr>
+
-
              <td>Power your iGEM projects with Cell-Free Systems!<br>
+
-
See what CFS can do to meet your project specifications, and the range of options available. (<a href="https://2007.igem.org/Imperial/Cell-Free/Whatis">more</a>...)
+
-
              </td>
+
   </table>
   </table>
-
        </div>
+
 
-
<div class="post-it bluebox">
+
-
<h2><b><a href="http://www.openwetware.org/wiki/IGEM:IMPERIAL/2007" title="">Full Documentation on OWW</a></b></h2>
+
</div>
</div>
Line 225: Line 184:
               IC Faculty of Engineering<br>
               IC Faculty of Engineering<br>
               IC Faculty of Natural Sciences<br>
               IC Faculty of Natural Sciences<br>
-
               European Commission, Synbiocomm Project<br><br>
+
               European Commission, Synbiocomm Project<br>
-
              <a href="http://www.geneart.com"><img src="http://www.geneart.com/fileadmin/templates/img/logo.gif" width="180"></a>
+
               </td>
               </td>
   </table>
   </table>

Latest revision as of 03:34, 27 October 2007

Welcome!

The IC GEMs team consists of ten 2nd year undergraduates from Bioengineering and Bioscience. Our genuine collective interest in healthcare led to the targetting of health and medicine related applications this year. Together with the vision of an industry, the strategy we adopted for our projects is to use the Engineering Cycle to create reliable Synthetic Biology products where standards and quality control are strictly kept.

Main Project - Infector Detector

Infector Detector is a system that will detect the presence of biofilm infections on urinary catheters by reporting on the presence of AHL, a signalling molecule used by E.coli, and output a fluorescent protein as a result. (more...)

Main Achievements

  • Designed and modelled a device to detect biofilms and prevent urinary catheter infections like MRSA
  • Successfully utilized cell-free chassis for Infector Detector
  • Characterised Infector Detector to detect AHL at ambient temperatures
  • Compared system expression to AHL Receiver (BBa_F2620) transfer function.

Foundational technology - Cell-Free Systems


Power your iGEM projects with Cell-Free Systems! Find out what this new chassis has done for us, and what it can do for you! (more...)

Sub Project - Cell by Date

Cell by Date will report when ground beef has been out of the cold chain for too long. It produces fluorescent proteins at ambient temperatures above 8°C. (more...)

Main Achievements

  • Designed and modelled a device to indicate spoilage of meat/break in the cold chain via the thermal history of the system
  • Utilised project results to characterise cell-free chassis
  • Characterised pTet-GFP and pT7-GFP under isothermal conditions

Retrieved from "http://2007.igem.org/wiki/index.php/Imperial"